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p38 MAPK

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p38 MAPK

Chemical Structure Cat. No. Product Name CAS No.
ITX-5061 HCl Chemical Structure
 BCP30784 ITX-5061 HCl 1252679-52-9
ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1).
Pexmetinib Chemical Structure
 BCP28410 Pexmetinib 945614-12-0
Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38α and p38β, respectively, and can be used in the research of acute myeloid leukemia.
SD-06 Chemical Structure
 BCP21625 SD-06 271576-80-8
SD-06 is a MAPK p38 alpha inhibitor for the treatment of arthritis.
SB202190 HCl Chemical Structure
 BCP21617 SB202190 HCl 350228-36-3
SB 202190 inhibits p38 and p38β2 with IC50 values of 50 nM and 100 nM. respectively.
R1487 Chemical Structure
 BCP29574 R1487 449811-92-1
R1487 is a p38 MAP kinase inhibitor with an IC50 of 10nM.
UM164 Chemical Structure
 BCP29207 UM164 903564-48-7
UM164 is a movel potent, dual c-Src/p38 with Kd of 2.7 nM (c-Src), potently inhibits both p38α and p38β; inhibits c-Src autophosphorylation in TNBC cell lines.
VX 702 Chemical Structure
 BCP28564 VX 702 745833-23-2
VX-702, one of a series of second-generation, is an orally active p38 MAP kinase inhibitors, for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases.
SB-681323 Chemical Structure
 BCP23819 SB-681323 444606-18-2
SB-681323, also known as Dilmapimod and GW-681323 , is p38 MAPK inhibitor.
p38 MAPK-IN-1 Chemical Structure
 BCP24818 p38 MAPK-IN-1 1006378-90-0
p38 MAPK-IN-1 is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM, shows sustained levels, low clearance and good bioavailability.
Dehydrocorydaline chloride Chemical Structure
 BCP24819 Dehydrocorydaline chloride 10605-03-5
Dehydrocorydaline chloride is an alkaloidal that has anti-inflammatory and anti-cancer activities.
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