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BTK

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BTK

Chemical Structure Cat. No. Product Name CAS No.
Pirtobrutinib Chemical Structure
 BCP42730 Pirtobrutinib 2101700-15-4
Pirtobrutinib is a Bruton's tyrosine kinase (BTK) inhibitor and antineoplastic agent.
CNX-500 Chemical Structure
 BCP40963 CNX-500 1202758-21-1
CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin.
Olmutinib dihydrochloride Chemical Structure
 BCP38296 Olmutinib dihydrochloride 1842366-97-5
Olmutinib is an orally available, mutant-selective third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) that is being developed for treatment of advanced and metastatic EGFR mutation-positive non-small cell lung cancer (NSCLC).
Orelabrutinib Chemical Structure
 BCP37603 Orelabrutinib 1655504-04-3
Orelabrutinib is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor, being developed by InnoCare Pharma, for the treatment of chronic lymphocytic leukaemia.
Remibrutinib Chemical Structure
 BCP36887 Remibrutinib 1787294-07-8
Remibrutinib, also known as LOU064, is a Bruton's tyrosine kinase inhibitor.
Btk inhibitor 1 R enantiomer hydrochloride Chemical Structure
 BCP30305 Btk inhibitor 1 R enantiomer hydrochloride 1553977-42-6
Btk inhibitor 1R enantiomer Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.
QL47 Chemical Structure
 BCP30763 QL47 1469988-75-7
QL47 is a potent, selective and irreversible BTK kinase inhibitor with IC50 of 7 nM.
BMX-IN-1 Chemical Structure
 BCP30306 BMX-IN-1 1431525-23-3
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
PCI-29732 Chemical Structure
 BCP30138 PCI-29732 330786-25-9
PCI-29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
(R)-Zanubrutinib Chemical Structure
 BCP30082 (R)-Zanubrutinib 1691249-44-1
(R)-Zanubrutinib is the R enantiomer of Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (BTK) inhibitor.
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