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BTK

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BTK

Chemical Structure Cat. No. Product Name CAS No.
BMX-IN-1 Chemical Structure
 BCP30306 BMX-IN-1 1431525-23-3
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
PCI-29732 Chemical Structure
 BCP30138 PCI-29732 330786-25-9
PCI-29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
(R)-Zanubrutinib Chemical Structure
 BCP30082 (R)-Zanubrutinib 1691249-44-1
(R)-Zanubrutinib is the R enantiomer of Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (BTK) inhibitor.
Zanubrutinib Chemical Structure
 BCP29110 Zanubrutinib 1691249-45-2
Zanubrutinib is a potent, selective and orally available Bruton's tyrosine kinase (Btk) inhibitor.
Vecabrutinib Chemical Structure
 BCP29646 Vecabrutinib 1510829-06-7
Vecabrutinib, also known as SNS-062; FP-182, BSK-4841 and BIIB-062; is a potent, noncovalent, reversible BTK inhibitor that inhibits signaling through the BCR pathway.
BMS-986142 Chemical Structure
 BCP29622 BMS-986142 1643368-58-4
BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM.
BMS-986195 Chemical Structure
 BCP29496 BMS-986195 1912445-55-6
BMS-986195 is a potent, covalent, irreversible inhibitor of Bruton’s tyrosine kinase (BTK), with an IC50 of <1 nM.
ARQ-531 Chemical Structure
 BCP29029 ARQ-531 2095393-15-8
ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity.
Btk inhibitor 2 Chemical Structure
 BCP25149 Btk inhibitor 2 1558036-85-3
Btk inhibitor 2 is a Bruton's tyrosine kinase (BTK) inhibitor extracted from patent US 20170224688 A1.
Poseltinib Chemical Structure
 BCP29076 Poseltinib 1353562-97-2
Poseltinib, also known HM-71224 and LY3337641, is a tyrosine kinase inhibitor.
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