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Lipoxygenase

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Lipoxygenase

Chemical Structure Cat. No. Product Name CAS No.
Etalocib Chemical Structure
 BCP29555 Etalocib 161172-51-6
Etalocib, also known as LY293111 and VML295, is a novel diaryl ether carboxylic acid derivative, is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor.
Dehydroabietic acid Chemical Structure
 BCP18786 Dehydroabietic acid 1740-19-8
Dehydroabietic acid is an abietane diterpenoid that is abieta-8,11,13-triene substituted at position 18 by a carboxy group.
Abietic acid Chemical Structure
 BCP14376 Abietic acid 514-10-3
Abietic acid, an abietane diterpenoid, inhibited soybean 5-lipoxygenase with an IC50 of 29.5 ± 1.29 μM.
Malotilate Chemical Structure
 BCP01805 Malotilate 59937-28-9
Malotilate is a liver protein metabolism improved compound.
Cirsiliol Chemical Structure
 BCP28925 Cirsiliol 34334-69-5
Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.
Indirubin-3 Chemical Structure
 BCP14390 Indirubin-3 160807-49-8
Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and a less potent inhibitor of 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM.
Nordihydroguaiaretic acid Chemical Structure
 BCP08590 Nordihydroguaiaretic acid 500-38-9
Nordihydroguaiaretic acid is a 5-lipoxygenase (5LOX) (IC50=8±3 μM) and tyrosine kinase inhibitor.
ML355 Chemical Structure
 BCP28954 ML355 1532593-30-8
ML355 is a potent and selective inhibitor of human 12-lipoxygenase.
U-73122 Chemical Structure
 BCP12870 U-73122 112648-68-7
U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase).
Zileuton Chemical Structure
 BCP16199 Zileuton 111406-87-2
Zileuton(N-1(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea, A-64077) is a selective and potent 5-LO inhibitor, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation.
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