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GPCR/G Protein

Chemical Structure Cat. No. Product Name CAS No.
Darusentan Chemical Structure
BCP13024 Darusentan 171714-84-4
Darusentan (LU-135252; HMR-4005) is an endothelin receptor antagonist.
GGTI-2418 Chemical Structure
BCP30523 GGTI-2418 501010-06-6
GGTI-2418 is a synthetic peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase I) that appears to induce apoptosis by downregulating several pivotal oncogenic and tumor survival pathways.
Icatibant Chemical Structure
BCP19031 Icatibant 130308-48-4
Icatibant (HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
Hydroxy Bosentan Chemical Structure
BCP15832 Hydroxy Bosentan 253688-60-7
Hydroxy Bosentan is a metabolite of Bosentan.
Beraprost sodium Chemical Structure
BCP06345 Beraprost sodium 88475-69-8
Beraprost sodium is a potent IP receptor agonist, inhibiting ADP-induced platelet aggregation and P-selectin expression.
Beraprost Chemical Structure
BCP10436 Beraprost 88430-50-6
Beraprost is an aliphatic alcohol.
CID-1067700 Chemical Structure
BCP06876 CID-1067700 314042-01-8
CID-1067700 is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM.
Talinolol Chemical Structure
BCP30483 Talinolol 57460-41-0
Talinolol is a beta(1)-adrenergic receptor antagonist and a probe drug for P-glycoprotein (P-gp) activity in humans.
PF-06291874 Chemical Structure
BCP24856 PF-06291874 1393124-08-7
PF-06291874 is a highly potent glucagon receptor antagonist. It displays low in vivo clearance and excellent oral bioavailability in both rats and dogs.
MRTX-1257 Chemical Structure
BCP30448 MRTX-1257 2206736-04-9
MRTX-1257 is an irreversible covalent inhibitor of KRAS G12C with antitumor efficacy.
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