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GPCR/G Protein

Chemical Structure Cat. No. Product Name CAS No.
Evatanepag sodium Chemical Structure
BCP32615 Evatanepag sodium 223490-49-1
Evatanepag is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.
BX471 hydrochloride Chemical Structure
BCP32594 BX471 hydrochloride 288262-96-4
BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
GPR120 Agonist 2 Chemical Structure
BCP32553 GPR120 Agonist 2 1234844-11-1
GPR120 Agonist 2 is a GPR120 agonist.
Mapracorat Chemical Structure
BCP32546 Mapracorat 887375-26-0
Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist.
LP-211 Chemical Structure
BCP32536 LP-211 1052147-86-0
LP-211 is a a selective agonist of the serotonin 5-HT7 receptor with a Ki value of 0.58 nM at rat cloned 5-HT7 receptors, and >300-fold selectivity over the 5-HT1A receptor.
PF-543 HCl Chemical Structure
BCP26198 PF-543 HCl 1706522-79-3
PF-543 HCl is the hydrochloride salt form of PF-543, a novel SphK1 inhibitor that could exhibit activity in induceing necrosis in human colorectal cancer cells in biological studies. IC50: 2 nM; Ki: 3.6 nM.
Pranoprofen Chemical Structure
BCP11947 Pranoprofen 52549-17-4
Pranoprofen is a non-steroidal anti-inflammatory drug used in ophthalmology.Pranoprofen is a PGE2 inhibitor with IC50 of 7.5 μM.
Omidenepag isopropyl Chemical Structure
BCP26206 Omidenepag isopropyl 1187451-19-9
Omidenepag Isopropyl (OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor.
RO-1138452 Chemical Structure
BCP26234 RO-1138452 221529-58-4
RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist.
DMPX Chemical Structure
BCP26239 DMPX 14114-46-6
DMPX is a selective A2 adenosine receptor antagonist.
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