Home   >  
Angiogenesis/Protein Tyrosine Kinase
  >  
Trk Receptor

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Trk Receptor

Chemical Structure Cat. No. Product Name CAS No.
CH7057288 Chemical Structure
BCP33760 CH7057288 2095616-82-1
CH7057288 is a potent and selective TRK inhibitor.
ONO7475 Chemical Structure
BCP33232 ONO7475 1646839-59-9
ONO-7475 is a potent and orally active Axl/Mer inhibitor. ONO-7475 targets and binds to both Axl and Mer, and prevents their activity.
LOXO-101 HCl salt Chemical Structure
BCP30585 LOXO-101 HCl salt 1919868-83-9
LOXO-101 is an orally available, tropomyosin receptor kinase (Trk) inhibitor, with potential antineoplastic activity.
LOXO195 R racemic Chemical Structure
BCP30220 LOXO195 R racemic 1350884-56-8
(6RS)-LOXO-195 is a potent and selective Trk tyrosine kinase inhibitor.The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
LOXO195 RS-isomer Chemical Structure
BCP30219 LOXO195 RS-isomer 2097002-59-8
The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
LM22B-10 Chemical Structure
BCP30139 LM22B-10 342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
PD90780 Chemical Structure
BCP16228 PD90780 77422-99-2
PD90780 is a nonpeptide inhibitor of NGF binding to p75NTR (IC50 ~ 1 μM in CHO cells); binds NGF, not p75NTR.
AZ-23 Chemical Structure
BCP01916 AZ-23 915720-21-7
AZ-23 is a potent and selective tyrosine kinase (Trk) inhibitor having potential for therapeutic utility in neuroblastoma and multiple other cancers.
PF-06273340 Chemical Structure
BCP29619 PF-06273340 1402438-74-7
PF-06273340 is a potent, selective, and peripherally restricted Pan-Trk Inhibitor with an excellent LipE profile (IC50 value: Trk-A = 6 nM; Trk-B = 4 nM; Trk-C = 3 nM).
Belizatinib Chemical Structure
BCP29521 Belizatinib 1357920-84-3
Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase.
123下一页共 23 条记录 1 / 3 页 
0086-15971444841