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Prostaglandin Receptor

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Prostaglandin Receptor

Chemical Structure Cat. No. Product Name CAS No.
TG4-155 Chemical Structure
 BCP25837 TG4-155 1164462-05-8
TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. It blocks the induced expression of inflammatory markers in microglial cells.
AM-211 Chemical Structure
 BCP32870 AM-211 1175526-27-8
AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
AH 23848 calcium salt Chemical Structure
 BCP26022 AH 23848 calcium salt 81496-19-7
AH 23848 calcium salt is a dual antagonist of TP1 and EP4 receptors.
NTP42 Chemical Structure
 BCP32720 NTP42 2055599-51-2
NTP42 is a thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609.
Evatanepag sodium Chemical Structure
 BCP32615 Evatanepag sodium 223490-49-1
Evatanepag is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.
Pranoprofen Chemical Structure
 BCP11947 Pranoprofen 52549-17-4
Pranoprofen is a non-steroidal anti-inflammatory drug used in ophthalmology.Pranoprofen is a PGE2 inhibitor with IC50 of 7.5 μM.
Omidenepag isopropyl Chemical Structure
 BCP26206 Omidenepag isopropyl 1187451-19-9
Omidenepag Isopropyl (OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor.
RO-1138452 Chemical Structure
 BCP26234 RO-1138452 221529-58-4
RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist.
Rebamipide Chemical Structure
 BCP12128 Rebamipide 111911-87-6
Rebamipide is an enhancer of mucosal defense, scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2.
Misoprostol acid Chemical Structure
 BCP32053 Misoprostol acid 112137-89-0
Misoprostol Acid is a cytoprotective prostaglandin PGE1 analogue.
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