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GPCR/G Protein
Prostaglandin Receptor

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Prostaglandin Receptor

Chemical Structure Cat. No. Product Name CAS No.
BGC-20-1531 Chemical Structure
BCP37893 BGC-20-1531 1186532-61-5
BGC-20-1531 is a EP4 antagonist for the treatment of acute migraine.
ONO-8130 Chemical Structure
BCP37875 ONO-8130 459841-96-4
ONO-8130 is an orally available EP1 receptor antagonist.
DG-041 Chemical Structure
BCP35669 DG-041 861238-35-9
DG 041 inhibits PGE2 facilitation of platelet aggregation in vitro and ex vivo. Displays good plasma and metabolic stability.
TG4-155 Chemical Structure
BCP25837 TG4-155 1164462-05-8
TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. It blocks the induced expression of inflammatory markers in microglial cells.
AM-211 Chemical Structure
BCP32870 AM-211 1175526-27-8
AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
AH 23848 calcium salt Chemical Structure
BCP26022 AH 23848 calcium salt 81496-19-7
AH 23848 calcium salt is a dual antagonist of TP1 and EP4 receptors.
NTP42 Chemical Structure
BCP32720 NTP42 2055599-51-2
NTP42 is a thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609.
Evatanepag sodium Chemical Structure
BCP32615 Evatanepag sodium 223490-49-1
Evatanepag is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.
Pranoprofen Chemical Structure
BCP11947 Pranoprofen 52549-17-4
Pranoprofen is a non-steroidal anti-inflammatory drug used in ophthalmology.Pranoprofen is a PGE2 inhibitor with IC50 of 7.5 μM.
Omidenepag isopropyl Chemical Structure
BCP26206 Omidenepag isopropyl 1187451-19-9
Omidenepag Isopropyl (OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor.
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