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Calcium Channel

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Calcium Channel

Chemical Structure Cat. No. Product Name CAS No.
Carboxyamidotriazole Orotate Chemical Structure
 BCP34906 Carboxyamidotriazole Orotate 187739-60-2
Carboxyamidotriazole Orotate is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate shows anti-tumor, anti-inflammatory and antiangiogenic effects.
Cav 2.2 blocker 1 Chemical Structure
 BCP34882 Cav 2.2 blocker 1 1567335-29-8
Cav 2.2 blocker 1 is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM.
Bepridil hydrochloride hydrate Chemical Structure
 BCP34263 Bepridil hydrochloride hydrate 74764-40-2
Bepridil is an amine Calcium channel antagonist that used to treat angina. But it is no longer sold in the United States. It may be a possible option in the treatment of atrial fibrillation.
Efonidipine hydrochloride ethanolate Chemical Structure
 BCP33396 Efonidipine hydrochloride ethanolate 111011-76-8
Efonidipine hydrochloride monoethanolate is a dual T-type and L-type calcium channel blocker (CCB).The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders.
Dantrolene Chemical Structure
 BCP33078 Dantrolene 7261-97-4
Dantrolene is a muscle relaxant used for treatment of chronic spasticity that differs from other commonly used muscle relaxants in acting peripherally on muscle, rather than centrally on the spinal cord or brain. Dantrolene can cause acute liver injury which can be severe and even fatal.
ZSET-1446 Chemical Structure
 BCP33073 ZSET-1446 887603-94-3
ZSET1446(ST-101) is a novel cognitive enhancer that significantly improves learning deficits in various types of Alzheimer disease (AD) models.
Aranidipine Chemical Structure
 BCP32584 Aranidipine 86780-90-7
Aranidipine is a calcium channel blocker which may positively affect ambulatory blood pressure.
Ziconotide Chemical Structure
 BCP29050 Ziconotide 107452-89-1
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
Diltiazem Chemical Structure
 BCP32159 Diltiazem 42399-41-7
Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure.
Bepridil hydrochloride Chemical Structure
 BCP29393 Bepridil hydrochloride 68099-86-5
Bepridil hydrochloride is a calcium channel blocker, with antianginal activity.
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