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VEGFR

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VEGFR

Chemical Structure Cat. No. Product Name CAS No.
Vorolanib Chemical Structure
 BCP30430 Vorolanib 1013920-15-4
Vorolanib, also known as CM-082 and X-82, is small molecule dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) with antiangiogenic and antineoplastic activities.
ODM-203 HCl Chemical Structure
 BCP30289 ODM-203 HCl ODM-203hcl
ODM-203 is a potent, selective, dual inhibitor of FGFR and VEGFR tyrosine kinases with approximately equal potency towards recombinant FGFR1, 2, 3 and 4, as well as VEGFR1, 2 and 3 (IC50=5-35 nM).
EG00229 Chemical Structure
 BCP30286 EG00229 1018927-63-3
EG00229 is a Neuropilin 1 (NRP1) receptor antagonist. EG00229 inhibits VEGFA binding to NRP1.
Bevacizumab Chemical Structure
 BCP07998 Bevacizumab 216974-75-3
Bevacizumab is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor A (VEGF-A).
AAL-993 Chemical Structure
 BCP18097 AAL-993 269390-77-4
AAL-993 is a highly potent inhibitor of VEGFR-1 (IC50 =130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM).
ODM-203 Chemical Structure
 BCP30030 ODM-203 1430723-35-5
ODM-203 is an orally available inhibitor of the human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs), with potential antiangiogenic and antineoplastic activities.
AST-487 Chemical Structure
 BCP21589 AST-487 630124-46-8
AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.
SU-5408 Chemical Structure
 BCP29247 SU-5408 15966-93-5
SU5408 is a potent and cell-permeable inhibitor of VEGFR2 kinase with an IC50 of 70 nM.
Oglufanide Chemical Structure
 BCP13098 Oglufanide 38101-59-6
Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis.
2-D08 Chemical Structure
 BCP18314 2-D08 144707-18-6
2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation.
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