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Porcupine

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Porcupine

Chemical Structure Cat. No. Product Name CAS No.
IWP-L6 Chemical Structure
BCP08956 IWP-L6 1427782-89-5
IWP L6 is a Porcn inhibitor with EC50 of 0.5 nM.
GNF-6231 Chemical Structure
BCP25768 GNF-6231 1243245-18-2
GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.
Wnt-C59 Chemical Structure
BCP07008 Wnt-C59 1243243-89-1
Wnt-C59 (C59) is a PORCN inhibitor for Wnt3A-mediated activation of a multimerized TCF-binding site driving luciferase with IC50 of 74 pM.
LGK-974 Chemical Structure
BCP08495 LGK-974 1243244-14-5
LGK974 is a highly potent, selective and orally bioavailable Porcupine inhibitor (Wnt signaling antagonist) with an IC50 <1 nM in the Wnt signaling reporter assay and Porcupine binding assay.
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