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BMI1

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BMI1

Chemical Structure Cat. No. Product Name CAS No.
PTC-028 Chemical Structure
BCP20909 PTC-028 1782970-28-8
A novel potent, selective, orally bioavailable BMI-1 inhibitor with potent anti-MM activity against primary MM cells (IC50=10-100 nM); decreases BMI-1 levels by posttranslational modification, selectively inhibits cancer cells in clonal growth and viability assays (IC50=100 nM), without effeccts on normal cells; exhibits significant antitumor activity in mouse model of ovarian cancer.
PTC-209 Chemical Structure
BCP09028 PTC-209 315704-66-6
PTC-209 is a potent and selective BMI-1 inhibitor, and results in irreversible reduction of cancer–initiating cells (CICs).
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