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JNK

Chemical Structure Cat. No. Product Name CAS No.
SU 3327 Chemical Structure
BCP32078 SU 3327 40045-50-9
SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM) with selectivity over p38 MAPK and Akt. SU 3327 inhibits the interaction between JNK and JIP (IC50 = 239 nM).
IQ-1S Chemical Structure
BCP17485 IQ-1S 23146-22-7
IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
CC-401 hydrochloride Chemical Structure
BCP25004 CC-401 hydrochloride 1438391-30-0
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.
DB-07268 Chemical Structure
BCP16456 DB-07268 929007-72-7
DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.
CC-401 Chemical Structure
BCP01960 CC-401 395104-30-0
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
BI-78D3 Chemical Structure
BCP17200 BI-78D3 883065-90-5
BI 78D3 is a competitive c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 280 nM that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K.
AstragalosideIV Chemical Structure
BCP28188 AstragalosideIV 84687-43-4
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
Tomatidine HCl Chemical Structure
BCP10953 Tomatidine HCl 6192-62-7
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling.
Tomatidine Chemical Structure
BCP13250 Tomatidine 77-59-8
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling.
JNK-IN-8 Chemical Structure
BCP09744 JNK-IN-8 1410880-22-6
JNK-IN-8 is a highly selective JNK inhibitor based on multiple profiling strategies.
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