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JNK

Chemical Structure Cat. No. Product Name CAS No.
Urolithin B Chemical Structure
BCP35736 Urolithin B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
DTP3 TFA Chemical Structure
BCP34038 DTP3 TFA DTP3
DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.
AS601245 Chemical Structure
BCP32871 AS601245 345987-15-7
AS601245 is a cell-permeable JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
SU 3327 Chemical Structure
BCP32078 SU 3327 40045-50-9
SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM) with selectivity over p38 MAPK and Akt. SU 3327 inhibits the interaction between JNK and JIP (IC50 = 239 nM).
IQ-1S Chemical Structure
BCP17485 IQ-1S 23146-22-7
IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
CC-401 hydrochloride Chemical Structure
BCP25004 CC-401 hydrochloride 1438391-30-0
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.
DB-07268 Chemical Structure
BCP16456 DB-07268 929007-72-7
DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.
CC-401 Chemical Structure
BCP01960 CC-401 395104-30-0
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
BI-78D3 Chemical Structure
BCP17200 BI-78D3 883065-90-5
BI 78D3 is a competitive c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 280 nM that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K.
AstragalosideIV Chemical Structure
BCP28188 AstragalosideIV 84687-43-4
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
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