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HIV

Chemical Structure Cat. No. Product Name CAS No.
Gardiquimod TFA Chemical Structure
 BCP30186 Gardiquimod TFA 1159840-61-5
Gardiquimod trifluoroacetate is a specific TLR7 agonist which can also inhibit HIV-1 reverse transcriptase.
Gardiquimod Chemical Structure
 BCP30187 Gardiquimod 1020412-43-4
Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier.
DL-Thioctic acid Chemical Structure
 BCP13221 DL-Thioctic acid 1077-28-7
Alpha-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation.
Nevirapine Chemical Structure
 BCP05587 Nevirapine 129618-40-2
Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM.
KP1461 Chemical Structure
 BCP23972 KP1461 943540-08-7
KP-1461 is a deoxycytidine analogue that is randomly inserted into HIV DNA by reverse transcriptase where it can cause base mispairing and introduce mutations that decrease viral fitness.
TAK-779 Chemical Structure
 BCP28073 TAK-779 229005-80-5
TAK-779 is a highly potent and selective nonpeptide CCR5 antagonist with a IC50 value of 1.4 nM in the binding assay, TAK-779 also inhibited the replication of macrophage (M)-tropic HIV-1 (Ba-L strain) in both MAGI-CCR5 cells and PBMCs with EC50 values of 1.2 and 3.7 nM, respectively.
Lavendustin B Chemical Structure
 BCP20779 Lavendustin B 125697-91-8
Lavendustin B is a Tyrosine Kinase Inhibitor amd an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).
AVX754 Chemical Structure
 BCP07907 AVX754 160707-69-7
Apricitabine, also known as (-)-BCH-10652; (-)-dOTC; AVX-754; BCH-10618; SPD-754, is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV.
MK-2048 Chemical Structure
 BCP03947 MK-2048 869901-69-9
MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
3-Deazaadenosine Chemical Structure
 BCP18416 3-Deazaadenosine 6736-58-9
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM; has anti-inflammatory, anti-proliferative and anti-HIV activity.
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