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TNF Receptor

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TNF Receptor

Chemical Structure Cat. No. Product Name CAS No.
Methylthiouracil Chemical Structure
BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
Shikonin Chemical Structure
BCP29329 Shikonin 517-89-5
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin has shown various biological activities, including inhibition of TNF-α, NF-κB, HIV-1.
C25-140 Chemical Structure
BCP30323 C25-140 1358099-18-9
C25-140 is the first in class protein-protein interaction inhibitor of a RING-E3 ligase (TRAF6) / E2 enzyme (Ubc13) binding.
Golimumab Chemical Structure
BCP30499 Golimumab 476181-74-5
Golimumab (CNTO 148) is a human monoclonal antibody which is used as an immunosuppressive drug. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor.
Etanercept Chemical Structure
BCP12862 Etanercept 185243-69-0
Etanercept is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.
AX-024 Chemical Structure
BCP30051 AX-024 1370544-73-2
AX-024 is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
AX-024 hydrochloride Chemical Structure
BCP30050 AX-024 hydrochloride 1704801-24-0
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
Tpl2 Kinase Inhibitor Chemical Structure
BCP16321 Tpl2 Kinase Inhibitor 871307-18-5
Tpl2 Kinase Inhibitor is a potent, selective, reversible and ATP-competitive inhibitor of Tpl2 kinase with IC50 of 50 nM.
Roquinimex Chemical Structure
BCP29884 Roquinimex 84088-42-6
Roquinimex (Linomide; PNU212616; ABR212616;LS 2616;FCF89) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.
S-99 Chemical Structure
BCP29577 S-99 1124381-69-6
S-99 is a novel inhibitor of LPS-induced TNFalpha release.
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