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Raw Materials
FLT3
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP30180 | MRX-2843 New | 1429882-07-4 |
MRX-2843 is an orally available small-molecule inhibitor of both MERTK and FLT3.
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BCP28052 | TG46 New | 936091-15-5 |
TG-46 is an inhibitor of JAK2, FLT3, RET, JAK3.
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BCP27919 | SB1317 New | 1204918-72-8 |
SB1317 is a potent inhibitor of CDK2, JAK2, and FLT3 for the treatment of cancer, with IC50 of 13, 73, and 56 nM for CDK2, JAK2 and FLT3, respectively.
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BCP21589 | AST-487 | 630124-46-8 |
AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.
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BCP29563 | CCT241736 | 1402709-93-6 |
CCT241736 is a novel, orally bioavailable, imidazo[4,5-b]pyridine derivative discovered at our Institute, highly selective for FLT3 and Aurora kinases with an S(10) selectivity score using KINOMEscan™ technology of 0.057 (fraction of 386 non-mutant kinases inhibited >90% when screened at 1 uM of CCT241736; San Diego, CA).
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BCP15254 | STK321130 | 923562-23-6 |
STK321130, also known as FLT3-IN-2, is potent FLT3 inhibitor.
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BCP16040 | SU5614 | 1055412-47-9 |
SU5614 is a potent and selective FLT3 inhibitor.
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BCP26188 | JNJ-47117096 | 1610586-62-3 |
MELK-T1 is a potent and selective inhibitor of protein kinase MELK. MELK-T1 decreases DNA-damage tolerance in proliferating cancer cells.
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BCP07984 | AZD-2932 | 883986-34-3 |
AZD2932 is a new series of quinazoline ether inhibitor which potently inhibits VEGFR-2 and PDGFR with IC50s of 4 nM/8 nM/ 7 nM for PDGFRβ/VEGFR-2/Flt-3.
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BCP14396 | AC-710 | 1351522-04-7 |
AC710 is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM/1.0 nM/1.3 nM/1.0 nM for FLT3/KIT/PDGFRα/PDGFRβ respectively.
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