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GABA Receptor

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GABA Receptor

Chemical Structure Cat. No. Product Name CAS No.
SAGE-217 Chemical Structure
BCP30027 SAGE-217 1632051-40-1
SAGE-217 is a potent GABAA receptor agonist with EC50s of 296 and 163 nM for α1β2γ2 and α4β3δ GABAA receptors, respectively.
Valerenic acid Chemical Structure
BCP20980 Valerenic acid 3569-10-6
Valerenic acid is a positive allosteric modulator of GABAA receptor.
Alprazolam Chemical Structure
BCP28608 Alprazolam 28981-97-7
Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) binding site on the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS).
Zolpidem hemitartrate Chemical Structure
BCP28267 Zolpidem hemitartrate 103188-50-7
Zolpidem is a benzodiazepine agonist with high selectivity for α1-subunit-containing GABAA receptors (BZ/ω1 site) and very high intrinsic activity.
Zolpidem Chemical Structure
BCP10205 Zolpidem 82626-48-0
Zolpidem is an inhibitory neurotransmitter, by binding to GABAA receptors at the same location as benzodiazepines.
Zolpidem Carboxylic Acid Chemical Structure
BCP10204 Zolpidem Carboxylic Acid 109461-65-6
Zolpidem Phenyl-4-carboxylic acid is the major urinary metabolite of zolpidem, accounting for 51% of an administered dose.
Zolpidem tartrate Chemical Structure
BCP28445 Zolpidem tartrate 99294-93-6
Zolpidem is a high-affinity positive modulator of GABAA receptors.
ONO-8590580 Chemical Structure
BCP29588 ONO-8590580 1802661-73-9
ONO-8590580 is a novel potent, selective GABAA α5 negative allosteric modulator, binds to the benzodiazepine binding sites on recombinant human α5-containing GABAA receptors with Ki of 7.9 nM.
AZD-7325 Chemical Structure
BCP29554 AZD-7325 942437-37-8
AZD-7325 is a GABA-Aα2,3 -selective receptor modulator.
Lorazepam Chemical Structure
BCP13713 Lorazepam 846-49-1
Lorazepam is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.
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