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GABA Receptor

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GABA Receptor

Chemical Structure Cat. No. Product Name CAS No.
Ganaxolone Chemical Structure
BCP30445 Ganaxolone 38398-32-2
Ganaxolone, also known as CCD 1042 and C1042, is a CNS-selective GABAA modulator that acts on well-characterized targets in the brain known to have anxiolytic and anticonvulsant effects. Ganaxolone protects against seizures in diverse animal models, including the pentylenetetrazol, 6 Hz and amygdala kindling models. Ganaxolone is a positive allosteric modulator of the action of the GABAA receptor and, unlike benzodiazepines, there does not appear to be tolerance to the anticonvulsant effects of ganaxolone.
Gaboxadol Hydrochloride Chemical Structure
BCP16610 Gaboxadol Hydrochloride 85118-33-8
Gaboxadol is a GABA agonist.
Aminooxyacetic acid Chemical Structure
BCP30347 Aminooxyacetic acid 645-88-5
Aminooxyacetic acid is a compound that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down.
Fluxametamide Chemical Structure
BCP30320 Fluxametamide 928783-29-3
Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls.
Tofisopam Chemical Structure
BCP09600 Tofisopam 22345-47-7
Tofisopam is a 2, 3-benzodiazepine drug which is a benzodiazepine derivative.
Estazolam Chemical Structure
BCP13317 Estazolam 29975-16-4
Estazolam is a benzodiazepine with anxiolytic, anticonvulsant, hypnotic, and muscle relaxant properties. Estazolam binds to the gamma-aminobutyric acid (GABA) receptor at a site distinct from the inhibitory neurotransmitter GABA binding site in the limbic system of the central nervous system.
Metomidate Chemical Structure
BCP12851 Metomidate 5377-20-8
Metomidate is an etomidate analogue.
Afoxolaner Chemical Structure
BCP21108 Afoxolaner 1093861-60-9
Afoxolaner is an isoxazoline that inhibits insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), blocking pre and post synaptic transfer of chloride ions across cell membranes.
Pikamilone Chemical Structure
BCP19066 Pikamilone 34562-97-5
Pikamilone is a drug formed by a synthetic combination of niacin and GABA.
Metadoxine Chemical Structure
BCP12135 Metadoxine 74536-44-0
Metadoxine is a selective antagonist of the serotonin receptor subtype 5-HT2B and displays high affinity to the gamma-aminobutyric acid (GABA) transporter.
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