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PROTAC

Chemical Structure Cat. No. Product Name CAS No.
PROTAC FKBP Degrader-3 Chemical Structure
BCP36792 PROTAC FKBP Degrader-3 2079056-43-0
PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader.
PROTAC AR Degrader-4 Chemical Structure
BCP36791 PROTAC AR Degrader-4 1351169-31-7
PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group.
KRAS G12C inhibitor 14 Chemical Structure
BCP36376 KRAS G12C inhibitor 14 2349393-95-7
KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 17, has an IC50 of 18 nM.
K-Ras Degrader-1 Chemical Structure
BCP36377 K-Ras Degrader-1 2378258-52-5
PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells.
BCL2 Degrader C5 Chemical Structure
BCP36383 BCL2 Degrader C5 2378801-85-3
BCL2 Degrader C5 is a novel potent and selective degrader of Bcl-2.
Azido-PEG3-maleimide Chemical Structure
BCP36238 Azido-PEG3-maleimide 1858264-36-4
Azido-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Lenalidomide-4-OH Chemical Structure
BCP36201 Lenalidomide-4-OH 1061604-41-8
Lenalidomide-Br Chemical Structure
BCP36200 Lenalidomide-Br 2093387-36-9
Lenalidomide-Br is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.
Lenalidomide-F Chemical Structure
BCP36199 Lenalidomide-F 2359705-88-5
VHL Ligand 3 Chemical Structure
BCP36198 VHL Ligand 3 1448189-98-7
VHL Ligand 3 is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology.
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