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PROTAC

Chemical Structure Cat. No. Product Name CAS No.
E3 Ligase Ligand-Linker Conjugates 52 (TFA) Chemical Structure
BCP32650 E3 Ligase Ligand-Linker Conjugates 52 (TFA) 2022182-58-5
E3 Ligase Ligand-Linker Conjugates 52 (TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
E3 Ligase Ligand-Linker Conjugates 2 Chemical Structure
BCP32649 E3 Ligase Ligand-Linker Conjugates 2 1818885-63-0
E3 Ligase Ligand-Linker Conjugates 2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
E3 ligase Ligand 1A Chemical Structure
BCP32648 E3 ligase Ligand 1A 1948273-02-6
E3 ligase Ligand 1A is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
A1874 Chemical Structure
BCP32647 A1874 2064292-12-0
A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells.
E3 ligase Ligand-Linker Conjugates 17 Chemical Structure
BCP32541 E3 ligase Ligand-Linker Conjugates 17 1950635-16-1
E3 Ligase Ligand-Linker Conjugates 17 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
dBET57 Chemical Structure
BCP32540 dBET57 1883863-52-2
dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2.
MS4078 Chemical Structure
BCP32539 MS4078 2229036-62-6
MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) with a Kd of 19 nM for binding affinity to ALK.
Pomalidomide-C2-NH2 hydrochloride Chemical Structure
BCP32542 Pomalidomide-C2-NH2 hydrochloride 2305369-00-8
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
QCA570 Chemical Structure
BCP32101 QCA570 2207569-08-0
QCA570 is a potent BET degrader based on PROTAC, with an IC50 of 10 nM for BRD4 BD1 Protein.
endo-BCN-PEG12-NHS ester Chemical Structure
BCP31909 endo-BCN-PEG12-NHS ester 2183440-26-6
endo-BCN-PEG12-NHS ester is a PEG derivative containing an NHS ester group and a BCN group.
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