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PROTAC

Chemical Structure Cat. No. Product Name CAS No.
CC-90009 Chemical Structure
BCP33889 CC-90009 1860875-51-9
CC-90009 is a cereblon (CRBN) E3 ligase modulator. Cereblon modulator 1 specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex. This leads to the ubiquitination of certain substrate proteins and induces the proteasome-mediated degradation of certain transcription factors, including Ikaros (IKZF1) and Aiolos (IKZF3).
Thalidomide-NH-C4-NH-Boc Chemical Structure
BCP33455 Thalidomide-NH-C4-NH-Boc 2093388-52-2
Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride Chemical Structure
BCP33454 Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride 2376990-30-4
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride Chemical Structure
BCP33452 Thalidomide-O-amido-PEG-C2-NH2 hydrochloride 2204226-02-6
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
Thalidomide-NH-C4-NH2 TFA Chemical Structure
BCP33453 Thalidomide-NH-C4-NH2 TFA 2093387-50-7
Thalidomide-NH-C4-NH2 TFA is an E3 ligase ligand-linker conjugate, and incorporates the Thalidomide based cereblon ligand and a linker.
Pomalidomide-amido-PEG3-C2-NH2 Chemical Structure
BCP33450 Pomalidomide-amido-PEG3-C2-NH2 2328070-52-4
Pomalidomide-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Chemical Structure
BCP33449 Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride 2245697-84-9
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Chemical Structure
BCP33448 Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride 2245697-85-0
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
Thalidomide-O-amido-C6-NH2 hydrochloride Chemical Structure
BCP33447 Thalidomide-O-amido-C6-NH2 hydrochloride 2376990-31-5
Thalidomide-O-amido-C6-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
Pomalidomide-PEG1-C2-N3 Chemical Structure
BCP33446 Pomalidomide-PEG1-C2-N3 2271036-44-1
Pomalidomide-PEG1-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology.
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