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PERK

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PERK

Chemical Structure Cat. No. Product Name CAS No.
HC-5404 Chemical Structure
BCP49422 HC-5404 HC-5404
HC-5404 is a differentiated, orally bioavailable investigational small molecule inhibitor of PERK (PKR-like endoplasmic reticulum kinase).
CCT020312 Chemical Structure
BCP44907 CCT020312 324759-76-4
CCT020312 is a selective EIF2AK3/PERK activator. CCT020312 elicits EIF2A phosphorylation in cells.
GSK2656157 Chemical Structure
BCP09007 GSK2656157 1337532-29-2
GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC50 of 0.9 nM.
GSK2606414 Chemical Structure
BCP06992 GSK2606414 1337531-36-8
GSK2606414 is an orally available, potent, and selective PERK inhibitor.
ISRIB (cis-isomer) Chemical Structure
BCP10786 ISRIB (cis-isomer) 548470-11-7
ISRIB is a potent inhibitor of PERK signaling.
ISRIB (trans-isomer) Chemical Structure
BCP23947 ISRIB (trans-isomer) 1597403-47-8
ISRIB trans-isomer is a potent inhibitor of PERK signaling, potently reverses the effects of eIF2α phosphorylation with IC50 of 5 nM.
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