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PARP

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PARP

Chemical Structure Cat. No. Product Name CAS No.
NU 1025 Chemical Structure
 BCP27646 NU 1025 90417-38-2
NU1025 is a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.
3-Aminobenzamide Chemical Structure
 BCP27669 3-Aminobenzamide 3544-24-9
3-Aminobenzamide is a competitive PARP inhibitor with Ki of 1.8 μM.
ME-0328 Chemical Structure
 BCP28104 ME-0328 1445251-22-8
ME0328 is a potent and selective ARTD3/PARP3 inhibitor with an IC50 of 0.89±0.28 μM.
Niraparib metabolite M1 Chemical Structure
 BCP24851 Niraparib metabolite M1 1476777-06-6
Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.
Niraparib Tosylate Monohydrate Chemical Structure
 BCP25472 Niraparib Tosylate Monohydrate 1613220-15-7
Niraparib Tosylate Monohydrate is an orally bioavailable, hydrated, tosylate salt form of niraparib, an inhibitor of poly (ADP-ribose) polymerase (PARP) types 1 and 2 (PARP-1 and -2), with antineoplastic activity.
JPI-289 2HCl.2H2O Chemical Structure
 BCP29656 JPI-289 2HCl.2H2O 1449233-60-6
JPI-289 hydrochloric hydrate is a novel potent, water soluble PARP-1 inhibitor with IC50 of 18.5 nM, inhibits cellular PAR formation with IC50 of 10.7 nM.
JPI-289 Chemical Structure
 BCP29659 JPI-289 1227156-72-0
JPI-289 is a poly-ADP-ribose polymerase inhibitor.
Talazoparib tosylate Chemical Structure
 BCP29084 Talazoparib tosylate 1373431-65-2
Talazoparib tosylate is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1.
NU 1085 Chemical Structure
 BCP24072 NU 1085 188106-83-4
NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs.
UPF-1069 Chemical Structure
 BCP27998 UPF-1069 1048371-03-4
UPF 1069 is a PARP inhibitor, with IC50s of 8 and 0.3 μM for PARP-1 and PARP-2, respectively.
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