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HSP

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HSP

Chemical Structure Cat. No. Product Name CAS No.
Debio 0932 Chemical Structure
BCP27980 Debio 0932 1061318-81-7
Debio 0932 is an orally active HSP90 inhibitor, with IC50s of 100 and 103 nM for HSP90α and HSP90β, respectively.
TRC 051384 Chemical Structure
BCP29281 TRC 051384 867164-40-7
TRC051384 is a heat shock protein 70 (HSP70) inducer.
TAS-116 Chemical Structure
BCP25132 TAS-116 1260533-36-5
TAS-114 is a first-in-class oral deoxyuridine triphosphatase (dUTPase) inhibitor, which acts as a modulator of the pyrimidine nucleotide metabolic pathway.
3-Methyltoxoflavin Chemical Structure
BCP30844 3-Methyltoxoflavin 32502-62-8
3-Methyltoxoflavin is a potent Protein disulfide isomerase (PDI) inhibitor, with an IC50 of 170 nM.
MKT-077 Chemical Structure
BCP30211 MKT-077 147366-41-4
MKT-077 is an inhibitor of mitochondrial hsp70 family member mortalin (mot-2), causing the selective death of cancer cells.
KNK437 Chemical Structure
BCP28527 KNK437 218924-25-5
KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.
PU-WS13 Chemical Structure
BCP27901 PU-WS13 1454619-14-7
PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 μM.
NMS-E973 Chemical Structure
BCP29502 NMS-E973 1253584-84-7
NMS-E973 is a novel, selective and potent inhibitor of heat shock protein 90 (Hsp90).
Gamitrinib Chemical Structure
BCP24917 Gamitrinib 1131626-46-4
G-TPP is a mitochondria-targeted Hsp90 inhibitor that increases cell death in HeLa and MCF7 cells, consistently inhibits cell death induced by oxidative stress and mitochondrial dysfunction induced by PINK1 mutation in mouse embryonic fibroblast cells and DA cell models such as SH-SY5Y and SN4741 cells.
MPC3100 Chemical Structure
BCP06949 MPC3100 958025-66-6
MPC-3100 is a n orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
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