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HSP

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HSP

Chemical Structure Cat. No. Product Name CAS No.
JG98 Chemical Structure
BCP31061 JG98 1456551-16-8
JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction.
Alvespimycin HCl Chemical Structure
BCP22705 Alvespimycin HCl 467214-21-7
Alvespimycin hydrochloride is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM.
Debio 0932 Chemical Structure
BCP27980 Debio 0932 1061318-81-7
Debio 0932 is an orally active HSP90 inhibitor, with IC50s of 100 and 103 nM for HSP90α and HSP90β, respectively.
TRC 051384 Chemical Structure
BCP29281 TRC 051384 867164-40-7
TRC051384 is a heat shock protein 70 (HSP70) inducer.
TAS-116 Chemical Structure
BCP25132 TAS-116 1260533-36-5
TAS-114 is a first-in-class oral deoxyuridine triphosphatase (dUTPase) inhibitor, which acts as a modulator of the pyrimidine nucleotide metabolic pathway.
3-Methyltoxoflavin Chemical Structure
BCP30844 3-Methyltoxoflavin 32502-62-8
3-Methyltoxoflavin is a potent Protein disulfide isomerase (PDI) inhibitor, with an IC50 of 170 nM.
MKT-077 Chemical Structure
BCP30211 MKT-077 147366-41-4
MKT-077 is an inhibitor of mitochondrial hsp70 family member mortalin (mot-2), causing the selective death of cancer cells.
KNK437 Chemical Structure
BCP28527 KNK437 218924-25-5
KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.
PU-WS13 Chemical Structure
BCP27901 PU-WS13 1454619-14-7
PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 μM.
NMS-E973 Chemical Structure
BCP29502 NMS-E973 1253584-84-7
NMS-E973 is a novel, selective and potent inhibitor of heat shock protein 90 (Hsp90).
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