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Wnt/Stem Cell

Chemical Structure Cat. No. Product Name CAS No.
Silmitasertib sodium Chemical Structure
BCP38774 Silmitasertib sodium 1309357-15-0
Silmitasertib sodium salt is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).
Pyrvinium pamoate Chemical Structure
BCP38435 Pyrvinium pamoate 3546-41-6
Pyrvinium pamoate is a naphthoic acid. It has a role as an anticoronaviral agent.
MYF-01-37 Chemical Structure
BCP33331 MYF-01-37 MYF-01-37
MYF-01-37 is a novel covalent inhibitor of TEAD targeting Cys380 when incubated with the TEAD2 protein.
KY19382 Chemical Structure
BCP38332 KY19382 2226664-93-1
KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively.
Epiblastin A Chemical Structure
BCP37885 Epiblastin A 16470-02-3
Epiblastin A is a Casein Kinase 1 (CK1) inhibitor. It converts epiblast stem cells (EpiSC) into embryonic stem cells (ESC) and enhances ESC self-renewal.
CMPD101 Chemical Structure
BCP37871 CMPD101 865608-11-3
CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively. CMPD101 can be used for the study of heart failure.
G244-LM Chemical Structure
BCP37837 G244-LM 1563007-08-8
G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization.
A-3 Hydrochloride Chemical Structure
BCP37347 A-3 Hydrochloride 78957-85-4
A-3 hydrochloride is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.
BRD0705 Chemical Structure
BCP33275 BRD0705 2056261-41-5
BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor. BRD0705 can be used for acute myeloid leukemia.
Adavivint Chemical Structure
BCP36799 Adavivint 1467013-03-3
Adavivint is a Wnt pathway inhibitor.
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