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Wnt/Stem Cell

Chemical Structure Cat. No. Product Name CAS No.
ABC-1183 Chemical Structure
BCP30547 ABC-1183 1042735-18-1
ABC-1183 is a selective dual GSK3α/β and CKD9 inhibitor.
BMS-986165 Chemical Structure
BCP30443 BMS-986165 1609392-27-9
BMS-986165 is a selective, potent, allosteric inhibitor of tyrosine kinase 2 (Tyk2).
Abrocitinib Chemical Structure
BCP30441 Abrocitinib 1622902-68-4
Abrocitinib, also known as PF-04965842, is an oral Janus Kinase 1 inhibitor being investigated for treatment of plaque psoriasis.
Adavivint Chemical Structure
BCP30409 Adavivint 1467093-03-3
Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.
CHF 5074 Chemical Structure
BCP30410 CHF 5074 749269-83-8
CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 μM, respectively.
JAK3-IN-6 Chemical Structure
BCP30249 JAK3-IN-6 1443235-95-7
JAK3-IN-6 is a potent, selective irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nM.
Rp-8-bromo-Cyclic AMPS sodium salt Chemical Structure
BCP29965 Rp-8-bromo-Cyclic AMPS sodium salt 925456-59-3
Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP.
BIO-acetoxime Chemical Structure
BCP27976 BIO-acetoxime 667463-85-6
BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity.
Baricitinib trifluoroacetate Chemical Structure
BCP16048 Baricitinib trifluoroacetate 1187594-10-0
Baricitinib, also known as INCB 028050 or LY 3009104, is an orally administered selective JAK1 andk JAK 2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK 2( 5.7 nM).
Halofuginone Hydrobromide Chemical Structure
BCP19376 Halofuginone Hydrobromide 64924-67-0
Halofuginone Hydrobromide is a potent prolyl-tRNA synthetase inhibitor.
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