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Wnt/Stem Cell

Chemical Structure Cat. No. Product Name CAS No.
BMS-906024 Chemical Structure
BCP18995 BMS-906024 1401066-79-2
BMS-906024 is a novel, potent Notch receptor inhibitor .
TX-1918 Chemical Structure
BCP16358 TX-1918 503473-32-3
TX-1918 is a cell-permeable tyrphostin derivative that inhibits eukaryotic elongation factor-2 kinase (eEF-2K; IC50 = 440 nM).
Robotnikinin Chemical Structure
BCP20109 Robotnikinin 1132653-79-2
Robotnikinin is an inhibitor of Shh signaling in a concentration-dependant manner.
FM-381 Chemical Structure
BCP29350 FM-381 2226521-65-7
FM-381 is a Chemical Probe For JAK3 and JAK3 specific reversible covalent inhibitor.
PTC-028 Chemical Structure
BCP20909 PTC-028 1782970-28-8
A novel potent, selective, orally bioavailable BMI-1 inhibitor with potent anti-MM activity against primary MM cells (IC50=10-100 nM); decreases BMI-1 levels by posttranslational modification, selectively inhibits cancer cells in clonal growth and viability assays (IC50=100 nM), without effeccts on normal cells; exhibits significant antitumor activity in mouse model of ovarian cancer.
PTC-209 Chemical Structure
BCP09028 PTC-209 315704-66-6
PTC-209 is a potent and selective BMI-1 inhibitor, and results in irreversible reduction of cancer–initiating cells (CICs).
JK184 Chemical Structure
BCP21568 JK184 315703-52-7
JK184 is a potent Hedgehog (Hh) pathway inhibitor with IC50 of 30 nM in mammalian cells.
GANT61 Chemical Structure
BCP08050 GANT61 500579-04-4
GANT 61 is a small molecule inhibitor of Gli1 and Gli2.
WIKI4 Chemical Structure
BCP15357 WIKI4 838818-26-1
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM).
Cercosporin Chemical Structure
BCP23993 Cercosporin 35082-49-6
Cercosporin is a potent, selective competitive PKC inhibitor.
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