Home   >  
TGF beta/Smad
  • Epigenetics
  >  
PKC

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

PKC

Chemical Structure Cat. No. Product Name CAS No.
UCN-01 Chemical Structure
BCP14345 UCN-01 112953-11-4
UCN-01 (7-hydroxystaurosporine) acts as an inhibitor against many phosphokinases, such as the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases.
UCN-02 Chemical Structure
BCP14344 UCN-02 121569-61-7
Prostratin Chemical Structure
BCP29895 Prostratin 60857-08-1
Prostratin is a protein kinase C activator. Inhibits growth and induces differentiation of AML cell lines.
Ingenol-3-angelate Chemical Structure
BCP10402 Ingenol-3-angelate 75567-37-2
Ingenol-3-angelate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
D-erythro-Sphingosine Chemical Structure
BCP24874 D-erythro-Sphingosine 123-78-4
D-erythro-Sphingosine is a inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.
Cercosporin Chemical Structure
BCP23993 Cercosporin 35082-49-6
Cercosporin is a potent, selective competitive PKC inhibitor.
ZIP Chemical Structure
BCP27697 ZIP 863987-12-6
ZIP is a novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance.
Ro 31-8220 mesylate Chemical Structure
BCP20982 Ro 31-8220 mesylate 138489-18-6
Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7.
Bisindoylmaleimide X HCl Chemical Structure
BCP20648 Bisindoylmaleimide X HCl 145317-11-9
Bisindolylmaleimide X hydrochloride is a potent and selective cell-permeable protein kinase C (PKC) inhibitor. Studies reveal that inhibition of PKCα by Bisindolylmaleimide X and other similar PKC inhibitors has been associated with enhanced cardiac contractility and protection from heart failure.
Bryostatin 1 Chemical Structure
BCP06923 Bryostatin 1 83314-01-6
Bryostatin 1 is a potent Protein Kinase C modulator isolated from the bryozoan Bugula neritina.
123下一页共 30 条记录 1 / 3 页 
0086-13720134139