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FXR

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FXR

Chemical Structure Cat. No. Product Name CAS No.
Nidufexor Chemical Structure
BCP28929 Nidufexor 1773489-72-7
Nidufexor is a farnesoid X receptor (FXR) agonist.
Cilofexor Chemical Structure
BCP29283 Cilofexor 1418274-28-8
Cilofexor is a farnesoid X receptor (FXR) agonist.
GW4064 Chemical Structure
BCP22751 GW4064 278779-30-9
GW 4064 is a potent FXR agonist with EC50 of 65 nM.
BAR502 Chemical Structure
BCP19638 BAR502 1612191-86-2
BAR502 is a dual FXR and GPBAR1 agonist with IC50 values of 2 μM and 0.4 μM, respectively.
Chenodeoxycholic acid Chemical Structure
BCP09679 Chenodeoxycholic acid 474-25-9
Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
Glycochenodeoxycholic acid sodium salt Chemical Structure
BCP17748 Glycochenodeoxycholic acid sodium salt 16564-43-5
Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
Sevelamer carbonate Chemical Structure
BCP13411 Sevelamer carbonate 845273-93-0
Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.
XL335 Chemical Structure
BCP08249 XL335 629664-81-9
WAY-362450 is a highly potent, selective, and orally active farnesoid X receptor agonist with an EC50 of 4 nM.
Tropifexor Chemical Structure
BCP20878 Tropifexor 1383816-29-2
Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).
Fexaramine Chemical Structure
BCP15784 Fexaramine 574013-66-4
Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity relative to natural compounds.
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