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DNA PK

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DNA PK

Chemical Structure Cat. No. Product Name CAS No.
AZD-7648 Chemical Structure
BCP30676 AZD-7648 2230820-11-6
AZD-7648 is a potent and highly selective DNA-PK inhibitor.
Nedisertib Chemical Structure
BCP30542 Nedisertib 1637542-33-6
Nedisertib (M3814) is a potent and selective inhibitor of DNA-dependent Protein Kinase (DNA-PK), with an IC50 of <3 nM.
VX984 Chemical Structure
BCP29470 VX984 1476074-39-1
VX984 is a DNA-PK inhibitor.
VX-984 Chemical Structure
BCP29319 VX-984 1562396-65-9
VX-984 is a selective DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 88±64 nM for A549 lung cancer cells.
PIK-75 Chemical Structure
BCP01968 PIK-75 372196-67-3
PIK-75, free base is a selective inhibitor of PI 3-kinase p110α (IC50 values are 5.8, 76 nM and 1.3 μM at PI 3-kinase p110α, PI 3-kinase p110γ and PI 3-kinase p110β respectively).
PIK-75 Hydrochloride Chemical Structure
BCP14766 PIK-75 Hydrochloride 372196-77-5
PIK-75 is a DNA-PK and PI3K inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively.
PIK75 Chemical Structure
BCP27614 PIK75 945619-31-8
PIK-75 is a DNA-PK and PI3K inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively.
PI-103 Chemical Structure
BCP01923 PI-103 371935-74-9
PI-103 is inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR.
PI-103 hydrobromide Chemical Structure
BCP19373 PI-103 hydrobromide PI-103
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.
IC-87114 Chemical Structure
BCP01922 IC-87114 371242-69-2
IC-87114 was the first isoform-selective PI3K inhibitor.
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