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CaSR

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CaSR

Chemical Structure Cat. No. Product Name CAS No.
Encaleret sulfate hydrate Chemical Structure
BCP49240 Encaleret sulfate hydrate ESH
Encaleret is an oral calcium-sensing receptor (CaSR) antagonist, for the treatment of osteoporosis.
Encaleret sulfate Chemical Structure
BCP49235 Encaleret sulfate 1214922-52-7
Encaleret is an oral calcium-sensing receptor (CaSR) antagonist, for the treatment of osteoporosis.
Etelcalcetide Chemical Structure
BCP25088 Etelcalcetide 1262780-97-1
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.
TNCA Chemical Structure
BCP48482 TNCA 42438-90-4
TNCA is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.
Evocalcet Chemical Structure
BCP33803 Evocalcet 870964-67-3
Evocalcet is an orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon administration, evocalcet allosterically binds to and inhibits the activity of CaR, thereby suppressing the production of serum parathyroid hormone (PTH) and prevents the PTH-mediated efflux of calcium from bone and normalizes calcium levels.
Etelcalcetide HCl Chemical Structure
BCP25093 Etelcalcetide HCl 1334237-71-6
Etelcalcetide, also known as AMG 416 and KAI-4169, is a D-amino peptide calcimimetic undergoing clinical evaluation for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis.
Ronacaleret HCl Chemical Structure
BCP11469 Ronacaleret HCl 702686-96-2
Ronacaleret, also known as SB751689, is an orally-active calcium-sensing receptor (CaSR) antagonist that has the potential for therapeutic utility in the stimulation of PTH release, notably as a bone anabolic agent comparable to recombinant human PTH(1-34) (rhPTH(1-34)).
SB-423562 Chemical Structure
BCP29936 SB-423562 351490-27-2
SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist.
Strontium chloride Chemical Structure
BCP28245 Strontium chloride 10025-70-4
Calcium sensing receptor (CaSR) agonist. Activates ERK1/2 signaling, intracellular calcium mobilization, and calcitonin secretion. Enhances osteogenic differentiation of mesenchymal stem cells.
Cinacalcet Chemical Structure
BCP07181 Cinacalcet 226256-56-0
AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism.
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