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DUB

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DUB

Chemical Structure Cat. No. Product Name CAS No.
SJB3-019A Chemical Structure
 BCP31485 SJB3-019A 2070015-29-9
SJB3-019A is a USP1 inhibitor.
GNE-6640 Chemical Structure
 BCP31358 GNE-6640 2009273-67-8
GNE-6640 is a novel selective USP7 inhibitor, inducing tumor cell death. GNE-6640 enhances cytotoxicity with chemotherapeutic agents and targeted compounds, including PIM kinase inhibitors.
USP25 and 28 inhibitor AZ-2 Chemical Structure
 BCP31313 USP25 and 28 inhibitor AZ-2 2165322-95-0
USP25 and 28 inhibitor AZ-2 is a potent, selective, dual USP25/28 inhibitor with IC50 of 0.9/0.9 uM, respectively.
USP25 and 28 inhibitor AZ-3 Chemical Structure
 BCP31314 USP25 and 28 inhibitor AZ-3 AZ-3
USP25 and 28 inhibitor AZ-1 Chemical Structure
 BCP31311 USP25 and 28 inhibitor AZ-1 2165322-94-9
AZ1 is a dual inhibitor of the USP25/28 deubiquitinating enzyme subfamily.
6-Thioguanine Chemical Structure
 BCP27718 6-Thioguanine 154-42-7
Thioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
TCID Chemical Structure
 BCP29983 TCID 30675-13-9
TCID is a DUB inhibitor for ubiquitin C-terminal hydrolase L3 with IC50 of 0.6 μM, 125-fold selective to L1.
HBX 41108 Chemical Structure
 BCP08394 HBX 41108 924296-39-9
HBX 41108 is an Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM).
SJB2-043 Chemical Structure
 BCP11060 SJB2-043 63388-44-3
SJB2-043 is one of analogs/derivatives of C527, which is a novel and potent USP1 (ubiquitin-specific protease 1) inhibitor.
NSC 632839 hydrochloride Chemical Structure
 BCP28077 NSC 632839 hydrochloride 157654-67-6
NSC 632839 is an Inhibitor of ubiquitin isopeptidase activity.
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