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Cytochrome P450

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Cytochrome P450

Chemical Structure Cat. No. Product Name CAS No.
PC945 Chemical Structure
BCP36481 PC945 1931946-73-4
PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively.
Clomethiazole Chemical Structure
BCP36337 Clomethiazole 533-45-9
Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus.
DMU2105 Chemical Structure
BCP35214 DMU2105 1031063-36-1
DMU2105(CYP1B1 inhibitor 7k) is a potent and specific CYP1B1 inhibitor.
Doxepin-d3 Hydrochloride Chemical Structure
BCP33258 Doxepin-d3 Hydrochloride 347840-07-7
Doxepin D3 Hydrochloride is a deuterium labeled Doxepin Hydrochloride.Doxepin is a tricyclic antidepressant (TCA) used for the treatment of major depression and anxiety.
Phillyrin Chemical Structure
BCP26036 Phillyrin 487-41-2
Phillyrin is a natural lignan that has the potential to ameliorate the inflammatory changes and insulin resistance in obese adipose tissue.
(R)-Talarozole Chemical Structure
BCP21218 (R)-Talarozole 870093-23-5
(R)-Talarozole is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid for the treatment of psoriasis and acne.
20(S)-Ginsenoside C-K Chemical Structure
BCP30926 20(S)-Ginsenoside C-K 39262-14-1
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
Abiraterone Acetate Chemical Structure
BCP02949 Abiraterone Acetate 154229-18-2
Abiraterone acetate(CB 7630) is a novel steroidal inhibitor of human Cytochrome P450(17α-Hydroxylase-C17,20-lyase).
Naringin Chemical Structure
BCP28297 Naringin 10236-47-2
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities.
Choline Fenofibrate Chemical Structure
BCP28592 Choline Fenofibrate 856676-23-8
Choline Fenofibrate (ABT-335) is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipidemia.
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