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Cytochrome P450

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Cytochrome P450

Chemical Structure Cat. No. Product Name CAS No.
(R)-Talarozole Chemical Structure
BCP21218 (R)-Talarozole 870093-23-5
(R)-Talarozole is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid for the treatment of psoriasis and acne.
20(S)-Ginsenoside C-K Chemical Structure
BCP30926 20(S)-Ginsenoside C-K 39262-14-1
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
Abiraterone Acetate Chemical Structure
BCP02949 Abiraterone Acetate 154229-18-2
Abiraterone acetate(CB 7630) is a novel steroidal inhibitor of human Cytochrome P450(17α-Hydroxylase-C17,20-lyase).
Naringin Chemical Structure
BCP28297 Naringin 10236-47-2
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities.
Choline Fenofibrate Chemical Structure
BCP28592 Choline Fenofibrate 856676-23-8
Choline Fenofibrate (ABT-335) is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipidemia.
DMU2105 Chemical Structure
BCP29862 DMU2105 1821143-79-6
DMU2105 is a potent and specific CYP1B1 inhibitor, with IC50s of 10, 742 nM for CYP1B1 and CYP1A1, respectively.
DMU-2139 Chemical Structure
BCP29861 DMU-2139 104890-70-2
DMU2139 is a CYP1B1 inhibitor.
Deferasirox Chemical Structure
BCP05341 Deferasirox 201530-41-8
Deferasirox is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.
Ketoconazole Chemical Structure
BCP28528 Ketoconazole 65277-42-1
Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
Talarozole Chemical Structure
BCP28256 Talarozole 201410-53-9
Talarozole is a potent inhibitor of both CYP26A1 and CYP26B1, with IC50 of 0.46 nM and 5.1 nM for CYP26B1 and CYP26A1, respectively.
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