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Nature products
Antibodies
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Intermediate
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Raw Materials
PPAR
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP37672 | Lobeglitazone New | 607723-33-1 |
Lobeglitazone is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic activity. Besides its activation of peroxisome proliferator-activated receptor (PPAR) gamma, lobeglitazone is also a potent agonist for PPARalpha.
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BCP35208 | GW6471 New | 880635-03-0 |
GW 6471 is a potent PPARα antagonist.
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BCP34904 | LY518674 New | 425671-29-0 |
LY518674 is a potent, selective PPARα antagonist, with an EC50 of 42 nM for human PPARα. LY518674 reduces triglycerides in and increased HDL-C and is used for the treatment of atherosclerosis.
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BCP33242 | GW6471 New | 436159-64-7 |
GW6471 is a potent PPARα antagonist.
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BCP33099 | Sipoglitazar New | 342026-92-0 |
Sipoglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.
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BCP23582 | Tesaglitazar New | 251565-85-2 |
Tesaglitazar is a PPAR agonist potentially for the treatment of type 2 diabetes. The drug had completed several phase III clinical trials, however in May, 2006 AstraZeneca announced that it had discontinued further development.
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BCP22942 | Pioditazone hydrochloride New | 112529-15-4 |
Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
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BCP30796 | MK 0767 New | 934017-32-0 |
MK 0767 is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, has been studied as a potential treatment of type 2 diabetes and dyslipidemia.
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BCP30365 | MA-0204 New | 2095128-17-7 |
MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD).
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BCP30326 | Darglitazone New | 141200-24-0 |
Darglitazone is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. Darglitazone may be able to abrogate acute cerebral inflammatory responses via its suppression of proinflammatory gene expression.
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