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PPAR

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PPAR

Chemical Structure Cat. No. Product Name CAS No.
Tesaglitazar Chemical Structure
 BCP23582 Tesaglitazar 251565-85-2
Tesaglitazar is a PPAR agonist potentially for the treatment of type 2 diabetes. The drug had completed several phase III clinical trials, however in May, 2006 AstraZeneca announced that it had discontinued further development.
Pioditazone hydrochloride Chemical Structure
 BCP22942 Pioditazone hydrochloride 112529-15-4
Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
MK 0767 Chemical Structure
 BCP30796 MK 0767 934017-32-0
MK 0767 is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, has been studied as a potential treatment of type 2 diabetes and dyslipidemia.
MA-0204 Chemical Structure
 BCP30365 MA-0204 2095128-17-7
MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD).
Darglitazone Chemical Structure
 BCP30326 Darglitazone 141200-24-0
Darglitazone is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. Darglitazone may be able to abrogate acute cerebral inflammatory responses via its suppression of proinflammatory gene expression.
Choline Fenofibrate Chemical Structure
 BCP28592 Choline Fenofibrate 856676-23-8
Choline Fenofibrate (ABT-335) is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipidemia.
Rosiglitazone hydrochloride Chemical Structure
 BCP28444 Rosiglitazone hydrochloride 302543-62-0
Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
Lanifibranor Chemical Structure
 BCP29124 Lanifibranor 927961-18-0
Lanifibranor is a peroxisome proliferator-activated receptors (PPAR) agonist.
Eupatilin Chemical Structure
 BCP09703 Eupatilin 22368-21-4
Eupatilin, a lipophilic flavonoid isolated from Artemisia species, is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.
(R) -ginsenoside Rh1 Chemical Structure
 BCP10284 (R) -ginsenoside Rh1 80952-71-2
Ginsenoside Rh1 is isolated from the root of Panax Ginseng. Ginsenoside Rh1 inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.
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