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SRPK

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SRPK

Chemical Structure Cat. No. Product Name CAS No.
SPHINX31 Chemical Structure
BCP30381 SPHINX31 1818389-84-2
SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) (IC50 value of 6 nM). It inhibits SRPK1 activity and phosphorylation of serine/arginine splicing factor 1 (SRSF1), increasing expression of the anti-angiogenic VEGF-A165b splice variant in retinal pigment epithelial (RPE) cells.
SRPIN340 Chemical Structure
BCP08400 SRPIN340 218156-96-8
SRPIN340 is a serine/arginine-rich protein kinase -specific inhibitor with an IC50 value of 0.89 uM .
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