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IDO

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IDO

Chemical Structure Cat. No. Product Name CAS No.
LY-3381916 Chemical Structure
BCP33269 LY-3381916 2166616-75-5
LY-3381916(IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
LM10 Chemical Structure
BCP31973 LM10 1316695-35-8
LM10 is a selective TDO inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively)
Norharmane Chemical Structure
BCP20998 Norharmane 244-63-3
Norharmane is a potent IDO inhibitor
NLG919 Chemical Structure
BCP09887 NLG919 1402836-58-1
GDC-0919, also known as NLG919 and RG6078, is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.
Epacadostat Chemical Structure
BCP14546 Epacadostat 1204669-58-8
Epacadostat is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM.
IDO-IN-1 Chemical Structure
BCP16681 IDO-IN-1 914638-30-5
IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM).
IDO-IN-8 Chemical Structure
BCP24965 IDO-IN-8 1402837-77-7
IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.
8-Nitrotryptanthrin Chemical Structure
BCP26220 8-Nitrotryptanthrin 77603-42-0
8-Nitrotryptanthrin is a potent human indoleamine 2,3-dioxygenase 2 (hIDO2) inhibitor which significantly reduces IDO2 activity with Ki of 0.97 μM.
PF-06840003 Chemical Structure
BCP17158 PF-06840003 198474-05-4
PF-06840003 is a highly selective orally bioavailable IDO-1 inhibitor.
Coptisine chloride Chemical Structure
BCP25760 Coptisine chloride 6020-18-4
Coptisine chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM.
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