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PD 1/PD L1

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PD 1/PD L1

Chemical Structure Cat. No. Product Name CAS No.
BMS-1166 hydrochloride Chemical Structure
BCP31309 BMS-1166 hydrochloride 2113650-05-6
BMS-1166 Hydrochloride is a potent PD-1/PD-L1 interaction inhibitor.
PD-1-IN-17 Chemical Structure
BCP31132 PD-1-IN-17 1673560-66-1
PD-1-IN-17 is a programmed cell death-1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM.
BMS-1166 Chemical Structure
BCP30748 BMS-1166 1818314-88-3
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM.
Durvalumab Chemical Structure
BCP25841 Durvalumab 1428935-60-7
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody that blocks the interaction of programmed cell death ligand 1 (PD-L1) with the PD-1 and CD80 (B7.1) molecules.
AUNP-12 Chemical Structure
BCP25139 AUNP-12 1353563-85-5
AUNP-12 is an immune checkpoint modulator and also a PD-1 pathway inhibitor.
Avelumab Chemical Structure
BCP25212 Avelumab 1537032-82-8
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity.
Atezolizumab Chemical Structure
BCP18055 Atezolizumab 1380723-44-3
Atezolizumab is a fully humanized, engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1).
PD-1-IN-1 Chemical Structure
BCP25947 PD-1-IN-1 1673534-76-3
PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO 2015033299 A1, compound example 4.
Nivolumab Chemical Structure
BCP28580 Nivolumab 946414-94-4
Nivolumab, marketed as Opdivo, is a humanized IgG4 anti-PD-1 monoclonal antibody used to treat cancer.
PD1-PDL1 inhibitor 1 Chemical Structure
BCP15801 PD1-PDL1 inhibitor 1 1675201-83-8
PD1-PDL1 inhibitor 1 is an inhibitor of the PD-1 /PD-Ll protein/protein interaction, is an immunomodulator.
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