Home   >  
Cell Cycle/DNA Damage
  >  
Topoisomerase

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Topoisomerase

Chemical Structure Cat. No. Product Name CAS No.
Phenoxodiol Chemical Structure
BCP34699 Phenoxodiol 81267-65-4
Phenoxodiol inhibits XIAP (an apoptosis inhibitor) and DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol activates the mitochondrial caspase system and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol is a synthetic analog of Genestein.
LMP744 Chemical Structure
BCP34017 LMP744 308246-52-8
LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
LMP744 hydrochloride Chemical Structure
BCP34016 LMP744 hydrochloride 308246-57-3
LMP744 hydrochloride is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
Indotecan Chemical Structure
BCP34018 Indotecan 915303-09-2
Indotecan is a novel selective and potent topoisomerase I inhibitor with potential anticancer activitity. Indotecan is currently in Phase I trials.
Chebulanin Chemical Structure
BCP28487 Chebulanin 166833-80-3
Chebulanin is isolated and purified from the fruits of Terminalia chebula
Dxd Chemical Structure
BCP32858 Dxd 1599440-33-1
Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).
VXc-​486 Chemical Structure
BCP20714 VXc-​486 1384984-18-2
VXc-486 is active against drug-resistant isolates, has bactericidal activity, and kills intracellular and dormant M. tuberculosis bacteria in a low-oxygen environment.
Banoxantrone dihydrochloride Chemical Structure
BCP31589 Banoxantrone dihydrochloride 252979-56-9
Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.
Exatecan Chemical Structure
BCP30802 Exatecan 171335-80-1
Exatecan is a water soluble topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
Daunomycinone Chemical Structure
BCP07437 Daunomycinone 21794-55-8
Daunomycinone is the aglycone of daunomycin.
123下一页末页共 68 条记录 1 / 7 页 
0086-15971444841