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Chemical Structure Cat. No. Product Name CAS No.
Namitecan Chemical Structure
BCP36777 Namitecan 372105-27-6
Namitecan is a potent topoisomerase I inhibitor, with antitumor property.
Exatecan mesylate dihydrate Chemical Structure
BCP36302 Exatecan mesylate dihydrate 197720-53-9
Exatecan Mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
Phenoxodiol Chemical Structure
BCP34699 Phenoxodiol 81267-65-4
Phenoxodiol inhibits XIAP (an apoptosis inhibitor) and DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol activates the mitochondrial caspase system and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol is a synthetic analog of Genestein.
LMP744 Chemical Structure
BCP34017 LMP744 308246-52-8
LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
LMP744 hydrochloride Chemical Structure
BCP34016 LMP744 hydrochloride 308246-57-3
LMP744 hydrochloride is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
Indotecan Chemical Structure
BCP34018 Indotecan 915303-09-2
Indotecan is a novel selective and potent topoisomerase I inhibitor with potential anticancer activitity. Indotecan is currently in Phase I trials.
Chebulanin Chemical Structure
BCP28487 Chebulanin 166833-80-3
Chebulanin is isolated and purified from the fruits of Terminalia chebula
Dxd Chemical Structure
BCP32858 Dxd 1599440-33-1
Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).
VXc-​486 Chemical Structure
BCP20714 VXc-​486 1384984-18-2
VXc-486 is active against drug-resistant isolates, has bactericidal activity, and kills intracellular and dormant M. tuberculosis bacteria in a low-oxygen environment.
Banoxantrone dihydrochloride Chemical Structure
BCP31589 Banoxantrone dihydrochloride 252979-56-9
Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.
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