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NOX

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NOX

Chemical Structure Cat. No. Product Name CAS No.
APX-115 Chemical Structure
BCP33883 APX-115 1270084-92-8
APX-115 is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively.
GSK2795039 Chemical Structure
BCP33870 GSK2795039 1415925-18-6
GSK2795039 is the first small molecule NADPH oxidase 2 (NOX2) inhibitor.
GKT136901 Chemical Structure
BCP32694 GKT136901 955272-06-7
GKT136901 is a NOX1/4 inhibitor.
Diphenyleneiodonium chloride Chemical Structure
BCP08692 Diphenyleneiodonium chloride 4673-26-1
Diphenyleneiodonium chloride is a NADPH oxidase (NOX) inhibitor and also functions as a TRPA1 activator with an EC50 of 1 to 3 μM.
VAS2870 Chemical Structure
BCP29113 VAS2870 722456-31-7
VAS2870 is a NADPH oxidase (NOX) inhibitor.
GLX351322 Chemical Structure
BCP30492 GLX351322 835598-94-2
GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M.
GKT137831 Chemical Structure
BCP14159 GKT137831 1218942-37-0
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 140±40 nM and 110±30 nM; a potent inhibitor of fibrosis and hepatocyte apoptosis.
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