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Protease/Metabolic Enzyme
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Chemical Structure Cat. No. Product Name CAS No.
UVI3003 Chemical Structure
BCP30351 UVI3003 847239-17-2
UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR), and inhibits xenopus and human RXRα in Cos7 cells, with IC50s of 0.22 and 0.24 μM, respectively.
LG100268 Chemical Structure
BCP08283 LG100268 153559-76-3
LG100268 is a potent and selective rexinoid and retinoid-X receptor (RXR) agonist. LG100268 binds to the α, β and γ RXR receptors with an IC50 = 3-4 nM and has no activity at the RAR retinoic acid receptors.
HX 531 Chemical Structure
BCP15618 HX 531 188844-34-0
HX 531 is an antagonist of retinoid X receptors.
All-trans-retinal Chemical Structure
BCP14368 All-trans-retinal 116-31-4
All-trans Retinal, also known as Vitamin A aldehyde or Retinaldehyde, is one of the many forms of vitamin A and also the oxidation product of all-trans retinol .
CD1530 Chemical Structure
BCP28865 CD1530 107430-66-0
CD-1530 is a retinoic acid receptor γ selective agonist.
(R)-2-Flurbiprofen Chemical Structure
BCP13426 (R)-2-Flurbiprofen 51543-40-9
(R)-Flurbiprofen is the R-enantiomer of the racemate NSAID Flurbiprofen, (R)-Flurbiprofen inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM.
LY2955303 Chemical Structure
BCP20655 LY2955303 1433497-19-8
LY2955303 is a potent and selective RAR-gamma antagonist for the treatment of osteoarthritis pain. LY2955303 has RAR-gamma Ki = 1.09 nM; RAR-alpha Ki > 1700 nM; RAR-beta Ki > 2980 nM. LY2955303 demonstrated good pharmacokinetic properties and was efficacious in the MIA model of osteoarthritis-like joint pain. LY2955303 demonstrated an improved margin to RAR -mediated adverse effects.
Acitretin Chemical Structure
BCP02080 Acitretin 55079-83-9
Acitretin is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
AR7 Chemical Structure
BCP25687 AR7 80306-38-3
AR7 is a retinoic acid receptor α (RARα) antagonist.
TTNPB Chemical Structure
BCP28362 TTNPB 71441-28-6
TTNPB is a selective and highly potent agonist of retinoic acid receptors (RAR) α, β, and γ.T
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