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S1P Receptor

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S1P Receptor

Chemical Structure Cat. No. Product Name CAS No.
FTY720 Acetic Acid Hydrochloride Chemical Structure
BCP31238 FTY720 Acetic Acid Hydrochloride 1346598-36-4
FTY720 is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.
GSK2018682 Chemical Structure
BCP31201 GSK2018682 1034688-30-6
GSK2018682 is a novel sphingosine-1-phosphate receptor 1 (s1p1) and 5 (s1p5) agonist.
S1P-agonist-1 Chemical Structure
BCP31070 S1P-agonist-1 1514888-56-2
S1p receptor agonist 1 is an S1P receptor agonist extracted from patent WO 2015039587 A1, compound example 2.
AKP-11 Chemical Structure
BCP29045 AKP-11 1220973-37-4
AKP-11 is a S1P1 agonist with immunomodulatory activities.
Ki16198 Chemical Structure
BCP07655 Ki16198 355025-13-7
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively.
CYM 5520 Chemical Structure
BCP24849 CYM 5520 1449747-00-5
CYM5520 is a pyrrolyl ketone derivative that acts as a potent, selective, allosteric agonist of sphingosine-1-phosphate receptor 2 (S1PR2; EC50 = 480 nM) that does not replace native ligand and its binding is not competitive with JTE-013.
LPA2 antagonist 1 Chemical Structure
BCP11072 LPA2 antagonist 1 1017606-66-4
LPA2 antagonist 3 is a selective inhibitor of LPA2 activity in with IC50 17 nM in vitro for inhibition of LPA(2) mediated Erk activation and proliferation of HCT-116 cells.
CYM-5541 Chemical Structure
BCP28983 CYM-5541 945128-26-7
CYM-5541 (ML249) is an selective and allosteric S1P3 receptor agonist with an EC50 between 72 and 132 nM.
Amiselimod Chemical Structure
BCP24738 Amiselimod 942399-20-4
Amiselimod, also known as MT1303, is a potent and selective immunosuppressant and sphingosine 1 phosphate receptor modulator.
ONO-7300243 Chemical Structure
BCP24850 ONO-7300243 638132-34-0
ONO-7300243 is a novel, potent lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 μM.
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