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Elastase

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Elastase

Chemical Structure Cat. No. Product Name CAS No.
Alvelestat Chemical Structure
BCP07945 Alvelestat 848141-11-7
Alvelestat (AZD9668) is a novel, oral inhibitor of neutrophil elastase (NE), an enzyme implicated in the signs, symptoms, and disease progression in NE-driven respiratory diseases such as bronchiectasis and chronic obstructive pulmonary disease via its role in the inflammatory process, mucus overproduction, and lung tissue damage.
GW311616 Chemical Structure
BCP11029 GW311616 198062-54-3
GW311616 is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM; free base form of GW311616A.
Sivelestat sodium tetrahydrate Chemical Structure
BCP09535 Sivelestat sodium tetrahydrate 201677-61-4
Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
Sivelestat Chemical Structure
BCP09708 Sivelestat 127373-66-4
Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse.
Sivelestat sodium Chemical Structure
BCP09709 Sivelestat sodium 150374-95-1
Sivelestat sodium(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse.
DMP-777 Chemical Structure
BCP02269 DMP-777 157341-41-8
DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.
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