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Neuro Signaling Pathway
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5 HT Receptor/Serotonin Receptor

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5 HT Receptor/Serotonin Receptor

Chemical Structure Cat. No. Product Name CAS No.
Ocaperidone Chemical Structure
BCP32651 Ocaperidone 129029-23-8
Ocaperidone is an effective antipsychotic agent, acting as a potent 5-HT2 and dopamine D2 antagonist, and a 5-HT1A agonist, with Kis of 0.14 nM, 0.46 nM, 0.75 nM, 1.6 nM and 5.4 nM for 5-HT2, a1-adrenergic receptor, dopamine D2, histamine H1 and a2-adrenergic receptor, respectively, and a pEC50 and pKi of 7.60 and 8.08 for h5-HT1A.
LP-211 Chemical Structure
BCP32536 LP-211 1052147-86-0
LP-211 is a a selective agonist of the serotonin 5-HT7 receptor with a Ki value of 0.58 nM at rat cloned 5-HT7 receptors, and >300-fold selectivity over the 5-HT1A receptor.
WAY-100635 Maleate Chemical Structure
BCP29013 WAY-100635 Maleate 1092679-51-0
WAY100635 Maleate is a potent, silent antagonist of serotonin 5-HT1A receptors.
Sarizotan Chemical Structure
BCP32062 Sarizotan 177975-08-5
Sarizotan, also known as EMD-128130, is a Dopamine D2 receptor partial agonist and Serotonin 1A receptor agonist.
SAM-315 Chemical Structure
BCP31825 SAM-315 744218-85-7
SAM-31 is selective 5-Hydroxytryptamine-6 Antagonists
F-15599 Chemical Structure
BCP31490 F-15599 635323-95-4
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist, with Ki of 3.4 nM.
Befiradol Chemical Structure
BCP31302 Befiradol 208110-64-9
Befiradol is a selective 5-HT1A receptor agonist.
(R,R)-Palonosetron Hydrochloride Chemical Structure
BCP21463 (R,R)-Palonosetron Hydrochloride 135729-75-8
(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron.
Venlafaxine Hydrochloride Chemical Structure
BCP21401 Venlafaxine Hydrochloride 99300-78-4
Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.
Deramciclane Chemical Structure
BCP21344 Deramciclane 120444-71-5
Deramciclane has a high affinity for 5-HT2A and 5-HT2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist.
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