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5 HT Receptor/Serotonin Receptor

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5 HT Receptor/Serotonin Receptor

Chemical Structure Cat. No. Product Name CAS No.
Azaphen 2HCl Chemical Structure
BCP27680 Azaphen 2HCl 24853-80-3
Azafen is a tricyclic antidepressant.It acts as a potent inhibitor of the reuptake of serotonin.
Ansofaxine hydrochloride Chemical Structure
BCP31009 Ansofaxine hydrochloride 916918-84-8
Ansofaxine hydrochloride is a triple reuptake inhibitor of serotonin (IC50= 723 nM), dopamine (IC50= 491 nM) and norepinephrine reuptake (IC50= 763 nM).
Tropisetron Chemical Structure
BCP27620 Tropisetron 89565-68-4
Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
Nefazodone Chemical Structure
BCP30990 Nefazodone 83366-66-9
Nefazodone is a selective serotonin 5-HT2 receptor antagonist. It is an antidepressant under the development of Bristol-Myers Squibb. Its sale was discontinued in some countries due to the rare incidence of hepatotoxicity.
Urapidil HCl Chemical Structure
BCP23389 Urapidil HCl 64887-14-5
Urapidil HCl is an α1-adrenoceptor antagonist and 5-HT1A receptor agonist.
Mirtazapine Chemical Structure
BCP22244 Mirtazapine 85650-52-8
Mirtazapine is an atypical antidepressant with noradrenergic and specific serotonergic activity. It works by blocking the α2 adrenergic auto- and heteroreceptors (enhancing serotonin release), and selectively antagonizing the 5-HT2 and 5-HT3 serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5-HT1 receptor and blocks the histaminergic (H1) and muscarinic receptors. Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor.
Pizotifen malate Chemical Structure
BCP21824 Pizotifen malate 5189-11-7
Pizotifen, also known as Pizotyline, is a benzocycloheptene-based drug used as a medicine, primarily as a preventative to reduce the frequency of recurrent migraine headaches. Pizotifen is a serotonin antagonist acting mainly at the 5-HT2A and 5HT2C receptors. It also has some activity as an antihistamine as well as some anticholinergic activity.
Sibutramine Chemical Structure
BCP08127 Sibutramine 106650-56-0
Sibutramine is a novel 5-HT (serotonin) and noradrenaline reuptake inhibitor (SNRI).
RS-127445 Chemical Structure
BCP02714 RS-127445 199864-87-4
RS 127445 is a potent, selective and high affinity serotonin 5-HT2B receptor antagonist with a pIC50 of 10.4.
N-Desmethylclozapine Chemical Structure
BCP30683 N-Desmethylclozapine 6104-71-8
Norclozapine, also known as ACP-104, is a 5-HT2A inverse/dopamine/muscarinic receptor agonist potentially for the treatment of schizophrenia.
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