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RIP

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RIP

Chemical Structure Cat. No. Product Name CAS No.
GSK547 Chemical Structure
BCP30590 GSK547 2226735-55-1
GSK547 is a highly selective and potent inhibitor of RIP1 kinase that targets RIP1 in vivo.
HS1371 Chemical Structure
BCP30268 HS1371 2158197-70-5
HS-1371 is a potent and ATP-competitive RIP3 inhibitor with an IC50 of 20.8 nM.
GSK481 Chemical Structure
BCP17262 GSK481 1622849-58-4
GSK481 is a Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitor (RIP1 inhibitor).
GSK2983559 Chemical Structure
BCP24219 GSK2983559 1423186-80-4
GSK2983559 is a selective receptor interacting protein 2 (RIP2) kinase inhibitor.
WEHI-345 Chemical Structure
BCP23889 WEHI-345 1354825-58-3
WEHI-345 is a potent and selective inhibitor of RIPK2, with IC50 of 0.13 μM.
GSK583 Chemical Structure
BCP25523 GSK583 1346547-00-9
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 nM; rat in vivo PD IC50 = 50 nM).
 GSK872 Chemical Structure
BCP28887 GSK872 1346546-69-7
GSK872 (GSK2399872A) is a a receptor interacting protein kinase-3 (RIP3) inhibitor.
Necrostatin-1 Chemical Structure
BCP06760 Necrostatin-1 4311-88-0
Necrostatin-1 is an inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis.
GSK2982772 Chemical Structure
BCP25218 GSK2982772 1622848-92-3
GSK2982772 is a potent and ATP competitive RIP1 inhibitor with an IC50 of 16 nM.
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