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Interleukin Related

Chemical Structure Cat. No. Product Name CAS No.
F-901318 Chemical Structure
 BCP25872 F-901318 1928707-56-5
F-901318, also known as Olorofim, is a DHODH inhibitor potentially for the treatment of invasive aspergillosis.
AX-024 Chemical Structure
 BCP30051 AX-024 1370544-73-2
AX-024 is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
AX-024 hydrochloride Chemical Structure
 BCP30050 AX-024 hydrochloride 1704801-24-0
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
Cyanidin Chloride Chemical Structure
 BCP24007 Cyanidin Chloride 528-58-5
Cyanidin Chloride is a blocker of the cytokine interleukin-17A binding to the IL-17RA subunit to alleviate inflammation in vivo.
Secukinumab Chemical Structure
 BCP26257 Secukinumab 875356-43-7
Secukinumab is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A.
RCGD-423 Chemical Structure
 BCP29631 RCGD-423 108237-91-8
RCGD-423 is a modulator of gp130 signalling.
Ustekinumab Chemical Structure
 BCP20868 Ustekinumab 815610-63-0
Ustekinumab is a human monoclonal antibody used to treat psoriasis.
YM 90709 Chemical Structure
 BCP17183 YM 90709 163769-88-8
YM-90709 is a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.
GIT 27 Chemical Structure
 BCP09284 GIT 27 6501-72-0
Biological Activity Orally active immunomodulatory agent that primarily argets macrophages. Inhibits TNF-α secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 2/6 signaling pathway. Also reduces the secretion of pro-inflammatory cytokines IL1-β, IL-10 and IFN-γ. Antidiabetogenic; prevents IL-β and IFN-γ-induced pancreatic islet cell death in vitro.
Y320 Chemical Structure
 BCP09283 Y320 288250-47-5
Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.
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