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Sodium Channel

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Sodium Channel

Chemical Structure Cat. No. Product Name CAS No.
Lidocaine hydrochloride Chemical Structure
BCP30473 Lidocaine hydrochloride 73-78-9
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. Originally developed as a local anesthetic, it has properties as a class IB antiarrhythmic, a long-acting membrane stabilizing agent used against ventricular arrhythmia. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacine or prilocaine.
Flecainide Chemical Structure
BCP24373 Flecainide 54143-55-4
Flecainide is a synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold.
Chlorpromazine hydrochloride Chemical Structure
BCP30284 Chlorpromazine hydrochloride 69-09-0
Chlorpromazine Hydrochloride is an antagonist of the dopamine D2, 5HT2A, potassium channel and sodium channel. Chlorpromazine binds with D2 and 5HT2A with Kis of 363 nM and 8.3 nM, respectively.
Oxybuprocaine hydrochloride Chemical Structure
BCP13054 Oxybuprocaine hydrochloride 5987-82-6
Oxybuprocaine HCl is a local anesthetic used in ophthalmology to numb the surface of the eye for a variety of procedures.
Pilsicainide hydrochloride Chemical Structure
BCP09636 Pilsicainide hydrochloride 88069-49-2
Pilsicainide functions by blocking the fast inward movement of sodium ions through the Nav1.5 sodium channel that contributes to the rapid depolarization characteristic of phase 0 in the cardiac action potential.
Pilsicainide Chemical Structure
BCP13541 Pilsicainide 88069-67-4
Pilsicainide functions by blocking the fast inward movement of sodium ions through the Nav1.5 sodium channel that contributes to the rapid depolarization characteristic of phase 0 in the cardiac action potential.
Lidocaine Chemical Structure
BCP09081 Lidocaine 137-58-6
Lidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.
Lidocaine hydrochloride monohydrate Chemical Structure
BCP13499 Lidocaine hydrochloride monohydrate 6108-05-0
Lidocaine hydrochloride monohydrate is the hydrochloride monohydrate form of lidocaine, which is an aminoethylamide and a prototypical member of the amide class anesthetics.Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation.
Nicainoprol Chemical Structure
BCP30068 Nicainoprol 76252-06-7
Nicainoprol is a fast-sodium-channel blocking drug, which is a potent antiarrhythmic agent.
Tenapanor Chemical Structure
BCP24892 Tenapanor 1234423-95-0
Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively.
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