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DNA Methyltransferase

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DNA Methyltransferase

Chemical Structure Cat. No. Product Name CAS No.
CM-272 Chemical Structure
BCP32745 CM-272 1846570-31-7
CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and DNMTs in hematological malignancies.
Gamma-Oryzanol Chemical Structure
BCP13528 Gamma-Oryzanol 11042-64-1
Gamma-Oryzanol is a triterpenoid.
Lomeguatrib Chemical Structure
BCP07818 Lomeguatrib 192441-08-0
Inhibitor of O6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 μM in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo.
Zebularine Chemical Structure
BCP12209 Zebularine 3690-10-6
Zebularine(NSC309132; 4-Deoxyuridine) is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM.
RG108 Chemical Structure
BCP06930 RG108 48208-26-0
RG108 is a non-nucleoside DNA methyltransferase (DNMT) inhibitor.
SGI-1027 Chemical Structure
BCP09928 SGI-1027 1020149-73-8
SGI-1027 is a potent and selective inhibitor of DNA methyltransferase (DNMT) with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively.
5-Azacytidine Chemical Structure
BCP07496 5-Azacytidine 320-67-2
5-Azacytidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases.
Decitabine Chemical Structure
BCP02870 Decitabine 2353-33-5
Decitabine (NSC 127716; Dacogen; DAC)is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines.
Guadecitabine Chemical Structure
BCP28067 Guadecitabine 929901-49-5
Guadecitabine is a DNA methyltransferases (DNMT) inhibitor.
Guadecitabine sodium Chemical Structure
BCP24636 Guadecitabine sodium 929904-85-8
Guadecitabine, aslo known as SGI-110, is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity.