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HMGCR

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HMGCR

Chemical Structure Cat. No. Product Name CAS No.
Tert-butyl rosuvastatin Chemical Structure
BCP13063 Tert-butyl rosuvastatin 355806-00-7
Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin a selective, competitive HMG-CoA reductase inhibitor.
Rosuvastatin sodium Chemical Structure
BCP12749 Rosuvastatin sodium 147098-18-8
Rosuvastatin Sodium Salt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase
Pitavastatin lactone Chemical Structure
BCP11656 Pitavastatin lactone 141750-63-2
Pitavastatin (NK-104) is a potent HMG-CoA reductase inhibitor, Pitavastatin inhibited cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in a human liver cancer cell line (HepG2).
Clinofibrate Chemical Structure
BCP13269 Clinofibrate 30299-08-2
Clinofibrate is a hypelipidemic agent and a HMG-CoA reductase inhibitor.
Pravastatin sodium Chemical Structure
BCP13374 Pravastatin sodium 81131-70-6
Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Mevastatin Chemical Structure
BCP12101 Mevastatin 73573-88-3
Mevastatin (Compactin; ML236B) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans.
Pitavastatin Chemical Structure
BCP08462 Pitavastatin 147511-69-1
Pitavastatin (NK-104) is a potent HMG-CoA reductase inhibitor, Pitavastatin inhibited cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in a human liver cancer cell line (HepG2).
Pitavastatin calcium Chemical Structure
BCP04793 Pitavastatin calcium 147526-32-7
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting Nox. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187.
Fluvastatin Chemical Structure
BCP08213 Fluvastatin 93957-54-1
Fluvastatin is an HMGCR (HMG-CoA reductase) inhibitor.
Fluvastatin sodium salt Chemical Structure
BCP12844 Fluvastatin sodium salt 93957-55-2
Fluvastatin sodium is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), used to treat hypercholesterolemia and to prevent cardiovascular disease.
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