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Angiogenesis/Protein Tyrosine Kinase

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Chemical Structure Cat. No. Product Name CAS No.
ODM-203 Chemical Structure
BCP30030 ODM-203 1430723-35-5
ODM-203 is an orally available inhibitor of the human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs), with potential antiangiogenic and antineoplastic activities.
E-7090 Chemical Structure
BCP29727 E-7090 1622204-21-0
E7090 is an inhibitor of the fibroblast growth factor (FGF)/fibroblast growth factor receptor (FGFR) pathway, with potential antineoplastic activity.
S49076 HCl Chemical Structure
BCP29576 S49076 HCl 1265966-31-1
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo.
Dovitinib lactate Chemical Structure
BCP27905 Dovitinib lactate 692737-80-7
Dovitinib(CHIR-258; TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM.
H3B-6527 Chemical Structure
BCP17555 H3B-6527 1702259-66-2
H3B-6527 (H3 Biomedicine) is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.
NSC-12 Chemical Structure
BCP24324 NSC-12 102586-30-1
NSC-12, also known as NSC 172285, is an extracellular FGF trap with significant implications in cancer therapy.
TG 100801 Hydrochloride Chemical Structure
BCP25254 TG 100801 Hydrochloride 1018069-81-2
TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.
Derazantinib Chemical Structure
BCP29103 Derazantinib 1234356-69-4
Derazantinib (ARQ-087) is an ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC50s of 4.5, 1.8, and 4.5 nM, respectively.
SKLB610 Chemical Structure
BCP28112 SKLB610 1125780-41-7
SKLB610 is a VEGFR inhibitor with potent anti-tumor activity.
SUN11602 Chemical Structure
BCP19606 SUN11602 704869-38-5
SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity.
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