Home   >  
Angiogenesis/Protein Tyrosine Kinase
  >  
FAK

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

FAK

Chemical Structure Cat. No. Product Name CAS No.
PF 4618433 Chemical Structure
BCP29572 PF 4618433 1166393-85-6
PF 4618433 is an inhibitor of proline-rich tyrosine kinase 2 (PYK2) and focal adhesion kinase (FAK).
Y 11 Chemical Structure
BCP28812 Y 11 1086639-59-9
Y11 is a small molecule inhibitor targeting Y397 site of FAK.
TPX-0005 Chemical Structure
BCP19778 TPX-0005 1802220-02-5
TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 5.3 nM, 1.01 nM, 1.26 nM and 1.08 nM for SRC, WT ALK, ALK G1202R and ALK L1196M, respectively.
CEP-37440 Chemical Structure
BCP13227 CEP-37440 1391712-60-9
CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).
PF-562271 benzenesulfonate Chemical Structure
BCP14770 PF-562271 benzenesulfonate 939791-38-5
PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 13 nM, and has > 100-fold selectivity against other protein kinases, except for some CDKs.
GSK-2256098 Chemical Structure
BCP18311 GSK-2256098 1224887-10-8
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities.
Defactinib Chemical Structure
BCP11299 Defactinib 1073154-85-4
Defactinib is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
PF-04554878 Chemical Structure
BCP14401 PF-04554878 1345713-71-4
Defactinib, also known as VS-6063 and PF-04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities.
Defactinib hydrochloride Chemical Structure
BCP17737 Defactinib hydrochloride 1073160-26-5
Defactinib Hcl (VS-6063; PF-04554878) is a potent FAK phosphorylation inhibitor; overcomes YB-1–mediated paclitaxel resistance by an AKT-dependent pathway.
PND-1186 Chemical Structure
BCP10711 PND-1186 1061353-68-1
PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.
12下一页共 16 条记录 1 / 2 页 
0086-13720134139