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Beta catenin

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Beta catenin

Chemical Structure Cat. No. Product Name CAS No.
G244-LM Chemical Structure
 BCP37837 G244-LM 1563007-08-8
G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization.
NRX-252262 Chemical Structure
 BCP36626 NRX-252262 2438637-61-5
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM.
C-82 Chemical Structure
 BCP35612 C-82 1422253-37-9
C-82 is a second-generation specific CBP/β-catenin antagonist, which inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.
KY1220 Chemical Structure
 BCP34008 KY1220 292168-79-7
KY1220 is a small molecule that simultaneously degrades β-catenin and Ras by inhibition of the Wnt/β-catenin pathway.
Tegatrabetan Chemical Structure
 BCP32893 Tegatrabetan 1227637-23-1
Tegatrabetan is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1).
WIKI4 Chemical Structure
 BCP15357 WIKI4 838818-26-1
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM).
IQ-1 Chemical Structure
 BCP19305 IQ-1 331001-62-8
IQ-1 has many functions such as decreasing Wnt-stimulated phosphorylation, maintaining the pluripotency of murine ESCs, preventing PP2A/Nkd interaction and so on.
Cercosporin Chemical Structure
 BCP23993 Cercosporin 35082-49-6
Cercosporin is a potent, selective competitive PKC inhibitor.
Toxoflavin Chemical Structure
 BCP28886 Toxoflavin 84-82-2
PKF118-310 is a WNT-signaling modulator.
PRI-724 Chemical Structure
 BCP02465 PRI-724 847591-62-2
PRI-724 is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.
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