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Autophagy

Chemical Structure Cat. No. Product Name CAS No.
Schizandrin B Chemical Structure
BCP30085 Schizandrin B 61281-37-6
Schizandrin-B is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae, has been shown to produce antioxidant effect on rodent liver and heart.
ROC-325 Chemical Structure
BCP20110 ROC-325 1859141-26-6
ROC-325 is a novel inhibitor of autophagy.
Naringin Chemical Structure
BCP28297 Naringin 10236-47-2
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities.
Danshensu Chemical Structure
BCP28285 Danshensu 76822-21-4
Danshensu, a herbal preparation used in traditional Chinese medicine, possesses potential antitumor and anti‑angiogenesis effects.
Cycloheximide Chemical Structure
BCP28121 Cycloheximide 66-81-9
Cycloheximide is a eukaryote protein synthesis inhibitor and antibiotic.
IITZ-01 Chemical Structure
BCP29968 IITZ-01 1807988-47-1
IITZ-01 (Autophagy inhibitor IITZ-01) is a novel potent lysosomotropic autophagy inhibitor, exhibits >10-fold potent autophagy inhibition along with 12- to 20-fold better cytotoxic action than Chloroquine.
Fasudil Chemical Structure
BCP26821 Fasudil 103745-39-7
Fasudil, a Rho-kinase inhibitor, has been shown to reduce portal venous pressure in cirrhotic rats.
Fasudil hydrochloride Chemical Structure
BCP26351 Fasudil hydrochloride 105628-07-7
Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Kis of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
QX77 Chemical Structure
BCP29878 QX77 1798331-92-6
QX77 is a chaperone-mediated autophagy (CMA) activator.
LX-2343 Chemical Structure
BCP28952 LX-2343 333745-53-2
LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.
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