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Protease/Metabolic Enzyme
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Chemical Structure Cat. No. Product Name CAS No.
RGX-104 Chemical Structure
BCP31854 RGX-104 610318-54-2
RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene.
RGX-104 HCl Chemical Structure
BCP29451 RGX-104 HCl 610318-03-1
RGX-104 is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene.
BMS-779788 Chemical Structure
BCP20751 BMS-779788 918348-67-1
BMS-779788 is a LXR partial agonist with IC50 values of 68 nM for LXRα and 14 nM for LXRβ.
BMS-852927 Chemical Structure
BCP23542 BMS-852927 1256918-39-4
BMS-852927 is an LXRβ-selective agonist.
AZ-876 Chemical Structure
BCP19166 AZ-876 898800-26-5
AZ876 is a novel high-affinity LXR agonist. AZ876 was 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively.
SR-9243 Chemical Structure
BCP15765 SR-9243 1613028-81-1
SR9243 is a liver-X-receptor (LXR) inverse agonist that induces LXR-corepressor interaction.
LXR623 Chemical Structure
BCP03659 LXR623 875787-07-8
WAY-252623 (LXR-623) is a highly selective and orally bioavailable synthetic modulator of LXR.
WYE-672 Chemical Structure
BCP01904 WYE-672 1221265-39-9
A tissue selective liver X receptor (LXR) agonist.
T0901317 Chemical Structure
BCP03658 T0901317 293754-55-9
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively.
GW3965 HCl Chemical Structure
BCP03049 GW3965 HCl 405911-17-3
GW3965 is a liver X receptor full agonist on hLXRα and hLXRβ.