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Histone Methyltransferase

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Histone Methyltransferase

Chemical Structure Cat. No. Product Name CAS No.
GSK2807 Trifluoroacetate Chemical Structure
 BCP36148 GSK2807 Trifluoroacetate 2245255-66-5
GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM.
PF-06726304 Chemical Structure
 BCP32807 PF-06726304 1616287-82-1
PF-06726304 is a potent and selective EZH2 inhibitor with a Ki of 0.7 nM.
CM-272 Chemical Structure
 BCP32745 CM-272 1846570-31-7
CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and DNMTs in hematological malignancies.
Valemetostat Chemical Structure
 BCP31915 Valemetostat 1809336-39-7
Valemetostat, also known as DS-3201, is an antineoplastic drug candidate.
A-893 Chemical Structure
 BCP31184 A-893 1868232-32-9
A-893 is a cell-active inhibitor of Methyltransferase SMYD2, with an IC50 of 2.8 nM.
3-Deazaneplanocin A hydrochloride Chemical Structure
 BCP21084 3-Deazaneplanocin A hydrochloride 120964-45-6
3-Deazaneplanocin A hydrochloride is a potent histone methyltransferase EZH2 inhibitor.
Sinefungin Chemical Structure
 BCP28648 Sinefungin 58944-73-3
Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation .
BCI-121 Chemical Structure
 BCP30688 BCI-121 432529-82-3
BCI-121 is an SMYD3 inhibitor. It acts by impairing cancer cell growth.
HLCL-61 Chemical Structure
 BCP24221 HLCL-61 586395-74-6
HLCL-61 is a potent and selective PRMT5 inhibitor for treatment of acute myeloid leukemia.
Chemical Structure
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