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eIF

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eIF

Chemical Structure Cat. No. Product Name CAS No.
BTdCPU Chemical Structure
BCP31242 BTdCPU 1257423-87-2
BTdCPU is an activator of HRI. The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma.
A 484954 Chemical Structure
BCP28798 A 484954 142557-61-7
A 484954 is a selective inhibitor of eEF2K with IC50 value of 0.28 μM.
SBI-0640756 Chemical Structure
BCP23633 SBI-0640756 SBI-0640756
SBI-0640756 is a water soluble inhibitor of eIF4G1 and disrupts the eIF4F complex.
Briciclib Chemical Structure
BCP17292 Briciclib 865783-99-9
Briciclib is a water soluble derivative of ON 013100, and has the potential in targeting eIF4E for solid cancers.
Sal003 Chemical Structure
BCP08928 Sal003 1164470-53-4
Sal003A is a potent cell-permeable analog of the eIF2α phosphatase inhibitor .
4E1RCat Chemical Structure
BCP14974 4E1RCat 328998-25-0
4E1RCat is a dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction, and inhibits the binding of eIF4G to eIF4E with IC50 of 3.2 μM.
GCN2iB Chemical Structure
BCP29510 GCN2iB 2183470-12-2
GCN2iB is an ATP-competitive GCN2 inhibitor, with an IC50 of 2.4 nM.
4EGI-1 Chemical Structure
BCP28021 4EGI-1 315706-13-9
4EGI-1 is an inhibitor of eIF4E:eIF4G interaction that acts by preventing eIF4E binding to eIF4G.
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