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GPCR/G Protein
Melanocortin Receptor

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Melanocortin Receptor

Chemical Structure Cat. No. Product Name CAS No.
Afamelanotide acetate Chemical Structure
BCP35773 Afamelanotide acetate 1566590-77-9
Afamelanotide is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist used to?for Erythropoietic Protoporphyria.
Nonapeptide-1 Chemical Structure
BCP25057 Nonapeptide-1 158563-45-2
Nonapeptide-1, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Reduces synthesis of melanin and helps decrease skin pigmentation to a substantial degree.
THIQ Chemical Structure
BCP31597 THIQ 312637-48-2
THIQ is a potent and selective melanocortin 4 receptor agonist (2,3) (IC50= 1.2, 761 and 2067 nM for human MC4, MC3 and MC1 receptors respectively).
Adrenocorticotropic Hormone, Human Chemical Structure
BCP30218 Adrenocorticotropic Hormone, Human 12279-41-3
Adrenocorticotropic Hormone , human is a melanocortin receptor agonist. Sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe;SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF.
ACTH (1-39) (mouse, rat) Chemical Structure
BCP30334 ACTH (1-39) (mouse, rat) 77465-10-2
ACTH (1-39) (mouse, rat) is a potent melanocortin 2 (MC2) receptor agonist.
JNJ-10229570 Chemical Structure
BCP30848 JNJ-10229570 524923-88-4
JNJ-10229570 is a novel MC1R and MC5R antagonist was used to treat primary human sebaceous cells. It might have a potential for the treatment of acne and other sebaceous gland pathologies.