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Angiogenesis/Protein Tyrosine Kinase

Chemical Structure Cat. No. Product Name CAS No.
Abciximab Chemical Structure
BCP30526 Abciximab 143653-53-6
Abciximab is a glycoprotein IIb/IIIa receptor antagonist and a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery.
Necitumumab Chemical Structure
BCP30497 Necitumumab 906805-06-9
Necitumumab is a recombinant human IgG1 monoclonal antibody used as an antineoplastic.
Olaratumab Chemical Structure
BCP30495 Olaratumab 1024603-93-7
Olaratumab is a monoclonal antibody for the treatment of solid tumors.
TAS6417 Chemical Structure
BCP30474 TAS6417 1661854-97-2
TAS6417 is an EGFR inhibitor and an efficacious drug candidate for patients with NSCLC, with IC50 values ranging from 1.1-8.0 nM.
BMS-986165 Chemical Structure
BCP30443 BMS-986165 1609392-27-9
BMS-986165 is a selective, potent, allosteric inhibitor of tyrosine kinase 2 (Tyk2).
Abrocitinib Chemical Structure
BCP30441 Abrocitinib 1622902-68-4
Abrocitinib, also known as PF-04965842, is an oral Janus Kinase 1 inhibitor being investigated for treatment of plaque psoriasis.
Lazertinib Chemical Structure
BCP30440 Lazertinib 1903008-80-9
Lazertinib is a potent, highly mutant-selective, blood-brain barrier permeable, orally available and irreversible third-generation EGFR tyrosine kinase inhibitor, and can be used in the research of non-small cell lung cancer.
Vorolanib Chemical Structure
BCP30430 Vorolanib 1013920-15-4
Vorolanib, also known as CM-082 and X-82, is small molecule dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) with antiangiogenic and antineoplastic activities.
LOXO195 R racemic Chemical Structure
BCP30220 LOXO195 R racemic 1350884-56-8
The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
LOXO195 RS-isomer Chemical Structure
BCP30219 LOXO195 RS-isomer 2097002-59-8
The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
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