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Angiogenesis/Protein Tyrosine Kinase

Chemical Structure Cat. No. Product Name CAS No.
CH6953755 Chemical Structure
 BCP35548 CH6953755 2055918-71-1
CH6953755 is a potent, orally active and selective YES1 kinase (a member of the SRC family) inhibitor with an IC50 of 1.8 nM. CH6953755 inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo.
ARQ 197 Chemical Structure
 BCP28549 ARQ 197 1000873-98-2
ARQ-197 is a selective inhibitor of the c-Met receptor tyrosine kinase
TG-89 Chemical Structure
 BCP35054 TG-89 936091-56-4
TG-89 is an inhibitor of JAK2, FLT3, RET and JAK3.
RU-301 Chemical Structure
 BCP35046 RU-301 1110873-99-8
RU-301 is a novel pan-tam inhibitor, blocking the interface between tam ig1 ectodomain and gas6 lg domain, potently inhibiting axl reporter cell lines and native tam receptors cancer cell lines.
SAR131675 Chemical Structure
 BCP35024 SAR131675 1433953-83-3
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.
AG556 Chemical Structure
 BCP35023 AG556 133550-41-1
AG-556 is an epidermal growth factor receptor (EGFR) kinase inhibitor.
S49076 HCl Chemical Structure
 BCP35053 S49076 HCl 1265965-19-2
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
AIM-100 Chemical Structure
 BCP35051 AIM-100 873305-35-2
AIM-100 is a small molecule inhibitor of Ack1 with an IC50 of 24 nM
Acetyl-11-keto-beta-boswellic acid Chemical Structure
 BCP35036 Acetyl-11-keto-beta-boswellic acid 67416-61-9
Acetyl-11-keto-beta-boswellic acid is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
Bozitinib Chemical Structure
 BCP34901 Bozitinib 1440964-89-5
Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability.
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