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Angiogenesis/Protein Tyrosine Kinase

Chemical Structure Cat. No. Product Name CAS No.
Tyrosine kinase-IN-1 Chemical Structure
 BCP30849 Tyrosine kinase-IN-1 705946-27-6
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively.
ZD-4190 Chemical Structure
 BCP30854 ZD-4190 413599-62-9
ZD-4190 is a potent, orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling, used for the treatment of cancer.
BI-4464 Chemical Structure
 BCP30859 BI-4464 1227948-02-8
BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
QL47 Chemical Structure
 BCP30763 QL47 1469988-75-7
QL47 is a potent, selective and irreversible BTK kinase inhibitor with IC50 of 7 nM.
IRAK inhibitor 1 Chemical Structure
 BCP30783 IRAK inhibitor 1 1042224-63-4
IRAK inhibitor 1 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor.
Sennoside B Chemical Structure
 BCP14631 Sennoside B 128-57-4
Sennoside B, a kind of irritant laxative isolated from rhei rhizome, inhibits PDGF-stimulated cell proliferation.
Masitinib Mesylate Chemical Structure
 BCP30695 Masitinib Mesylate 1048007-93-7
Masitinib Mesylate is a potent and selective tyrosine kinase inhibitor that targets KIT.
TR-14035 Chemical Structure
 BCP30639 TR-14035 232271-19-1
TR-14035 is a a dual alpha4beta7(IC50=7 nM)/alpha4beta1 (IC50=87 nM) integrin antagonist .
A-770041 Chemical Structure
 BCP30674 A-770041 869748-10-7
A-770041 is selective and orally active Src-family Lck inhibitor; A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.
Ginsenoside-Rg5 Chemical Structure
 BCP10278 Ginsenoside-Rg5 186763-78-0
Ginsenoside Rg5 is a triterpenoid saponin. It has a role as a metabolite.
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